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| 灵丹菌质双向发酵工艺及药效品质研究 | |
| 引用本文： | 许晓燕,郑林用,李艳,江南,余梦瑶,罗霞.灵丹菌质双向发酵工艺及药效品质研究[J].中国食用菌,2010,29(2):28-31. |
| 作者姓名： | 许晓燕 郑林用 李艳 江南 余梦瑶 罗霞 |
| 作者单位： | 1. 四川省中医药科学院中药细胞与分子生物学实验室,四川,成都,610041 2. 四川省农业科学院,四川,成都,610066 3. 成都市经济信息中心,四川,成都,610041 |
| 基金项目： | 基金项目;省中医管理局项目;省应用基础项目 |
| 摘 要： | 采用双向固体发酵工程技术,以灵芝为发酵菌株,在含有不同比例丹参边角料的培养基中进行发酵,观察了不同培养基中菌丝的生长情况,测定了发酵产物（灵丹菌质）中多糖、蛋白质、三萜、丹参酮的含量变化,并研究了其提取物对小鼠活血化瘀功效的影响。结果表明灵丹菌质的最佳发酵组合为组合4,发酵40d,多糖含量26.48μg·g-1,蛋白质含量为397.24μg·g-1,灵芝酸三萜含量为4.92%。药效学实验显示,灵丹菌质组合4具有活血化瘀的药效,优于丹参药材。 |
| 关 键 词： | 灵芝 丹参边角料 双向发酵 药效品质 |
The Pharmacodynamic Action and Two-way Pattern Solid-state Fermentation of Ganoderma lucidum with Salvia miltiorrhiza Bunge By-product |
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| XU Xiao-yan,ZHENG Lin-Yong,LI Yan,JIANG Nan,YU Meng-yao,LUO Xia.The Pharmacodynamic Action and Two-way Pattern Solid-state Fermentation of Ganoderma lucidum with Salvia miltiorrhiza Bunge By-product[J].Edible Fungi of China,2010,29(2):28-31. | |
| Authors: | XU Xiao-yan ZHENG Lin-Yong LI Yan JIANG Nan YU Meng-yao LUO Xia |
| Institution: | XU Xiao-yan1,ZHENG Lin-Yong2,LI Yan3,JIANG Nan1,YU Meng-yao1,LUO Xia1 (1.Cellular , Molecular Lab of Chinese Materia Medica,Chengdu Sichuan 610041,2.Sichuan Academy of Agricultural Sciences,Chengdu Sichuan 610066,3.Chengdu Economic Information Center,Chengdu Sichuan 610064) |
| Abstract: | With two-way pattern solid-state fermentation technique, Ganoderma lucidum was fermented in the drug-containing medium containing different proportion of Salvia miltiorrhiza bunge by-product. Hyphal growth of G. lucidum was surveyed. The contents of polysaccharide, water-solubility protein, triterpene and tanshinton of solid-fermented products (SFP) were tested. In addition, the effect of activiting blood circulation to dissipate blood stasis on mouse fed with extracts was evaluated. The results showed that... |
| Keywords: | Ganoderma lucidum Salvia miltiorrhiza bunge by-product Two-way pattern solid-state fermentation Pharmacody- namic action |
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