| 维生素B 17对HepG2细胞体内外生长的影响 |
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| 引用本文： | 刘春刚,钱利纯,高玉鹏,曹崇海.维生素B 17对HepG2细胞体内外生长的影响[J].西北农业学报,2011,20(1):52-55. |
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| 作者姓名： | 刘春刚 钱利纯 高玉鹏 曹崇海 |
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| 作者单位： | 1. 西北农林科技大学,动物科技学院,陕西,杨凌,712100
2. 浙江大学动物科学学院,杭州,310029 |
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| 基金项目： | 浙江省重大科技专项农业项目(2008C12023-2) |
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| 摘 要： | 分别通过体外培养和体内接种试验,探讨维生素B-17对HepG2细胞体内外生长的影响。结果表明:体外试验中,当维生素B-17的添加量为1.3 g/L时,HepG2细胞生长抑制率仅为5.62%;当添加量为10.5 g/L时,抑制率增加到30.99%;当添加42 g/L时,抑制率达到56.30%。体内试验低质量浓度和中质量浓度组瘤块生长抑制均不明显,与对照组相比差异不显著(P>0.05);高质量浓度组对肿瘤生长抑制作用最好,与对照组相比差异显著(P<0.05)。说明高质量浓度的维生素B-17对HepG2细胞体内外生长均有抑制作用。
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| 关 键 词： | 维生素B-17 HepG2细胞 细胞培养 肿瘤 抑制 |
Effects of Vitamin B 17 on Growth of HepG2 Cells in Vivo and in Vitro Tests |
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| LIU Chungang,QIAN Lichun,GAO Yupeng and CAO Chonghai.Effects of Vitamin B 17 on Growth of HepG2 Cells in Vivo and in Vitro Tests[J].Acta Agriculturae Boreali-occidentalis Sinica,2011,20(1):52-55. |
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| Authors: | LIU Chungang QIAN Lichun GAO Yupeng and CAO Chonghai |
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| Institution: | LIU Chungang1,QIAN Lichun2,GAO Yupeng1 and CAO Chonghai2(1.College of Animal Science and Technology,Northwest A&F University,Yangling Shaanxi 712100,China,2.College of Animal Science,Zhejiang University,Hangzhou 310029,China) |
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| Abstract: | The tests in vivo and in vitro were conducted to study the effect of vitamin B-17 on the growth of HepG2 cells,The results showed that the cells growth inhibition rate is only 5.62% when vitamin B-17 adding amount is 1.3 g/L,30.99% when adding amount is 10.5 g/L,and 56.30% when adding amount is 42 g/L.In vivo test,compared with the control group,tumor size and weight of pieces is no significant difference(P>0.05) from low and middle concentration groups;the effect of high concentration group is the best,has... |
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| Keywords: | Vitamin B-17 HepG2 cells Cell culture Tumor Restrain |
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