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幼龄动物铁吸收及其调控
引用本文:孙效名,吴信,印遇龙,舒绪刚.幼龄动物铁吸收及其调控[J].动物营养学报,2012,24(6):1001-1006.
作者姓名:孙效名  吴信  印遇龙  舒绪刚
作者单位:1. 中国科学院亚热带农业生态研究所,湖南省畜禽健康养殖工程技术中心,中国科学院亚热带农业生态过程重点实验室,长沙410125
2. 广州九益生物技术有限公司,广州,510800
基金项目:广东省中国科学院全面战略合作项目(2011B090300006;2009B091300043);国家自然科学基金项目(31101730;30528006);中国科学院知识创新重要方向项目(XMXX281177;KSCX2-YW-N-051)
摘    要:哺乳动物机体内铁稳态的维持对生长发育非常重要,尤其是在幼龄快速生长阶段.铁的缺乏不仅严重影响幼龄动物的生长性能,而且会给中枢神经系统带来不可逆的损伤;但是机体铁过量也将对幼龄动物造成氧化应激并产生长期的副作用.动物机体在成年阶段对铁吸收过程能够精准地调控,但在幼龄阶段其铁调控功能并不成熟.幼龄动物小肠铁吸收的效率非常高,因此,对幼龄动物补铁需要慎重.本文就幼龄动物铁的吸收及其调控特点做一综述.

关 键 词:铁稳态  幼龄动物  吸收  铁过量  调控

Iron Absorption and Its Regulation in the Neonate
SUN Xiaoming , WU Xin , YIN Yulong , SHU Xugang.Iron Absorption and Its Regulation in the Neonate[J].Acta Zoonutrimenta Sinica,2012,24(6):1001-1006.
Authors:SUN Xiaoming  WU Xin  YIN Yulong  SHU Xugang
Institution:1.Hunan Provincial Engineering Research Center of Healthy Livestock,Key Laboratory of Agro-Ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha 410125,China; 2.Guangzhou Jiuyi Bio-Technology Co.,Ltd.,Guangzhou 510800,China)
Abstract:Maintaining iron homeostasis is important for mammal health,particularly in the rapidly growing period following birth.Iron deficiency not only decreases growth performance but also results in irreversible damage to central nervous system.However,the overload of iron during this period can also be detrimental,possibly due to excessive free radical production.However,neonates are unable to be down regulated in response to excess iron as it can be fine balanced in adults.So it is prudent to supplement neonates with iron as the immature regulation of iron absorption during early infancy.This article provides a succinct overview of current understanding of intestinal iron absorption and its regulation in the neonate.
Keywords:iron homeostasis  neonate  absorption  iron overload  regulation
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