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禾谷镰孢菌FgCYP51B蛋白Y137H影响分生孢子及子囊孢子发育
引用本文:迟梦宇,钱恒伟,赵颖,赵彦翔,黄金光.禾谷镰孢菌FgCYP51B蛋白Y137H影响分生孢子及子囊孢子发育[J].植物病理学报,2019,49(2):283-288.
作者姓名:迟梦宇  钱恒伟  赵颖  赵彦翔  黄金光
作者单位:青岛农业大学植物医学学院/ 山东省植物病虫害综合防控重点实验室,青岛 266109
基金项目:国家重点研发计划重点专项黄淮海冬小麦化肥农药减施技术集成研究与示范(2017YFD0201705);国家自然基金(31471735);山东省"泰山学者"建设工程专项经费(6631115038)
摘    要:<正>小麦赤霉病(Fusarium Head Blight,FHB),主要是由镰刀菌属真菌引起的一种流行性毁灭性病害。在世界各小麦种植区尤其是温暖潮湿和半潮湿地区发生最为严重~(1,2])。它不仅能够降低小麦产量,其染病麦粒中还会产生对人畜健康严重危害的真菌毒素~(3])。在不同的地区由于气候因素和地理环境的不同,分布着不同的致病菌株。在我国,

收稿时间:2018-05-16

The FgCYP51B Y137H mutation is important for conidiation and ascospore development in Fusarium graminearum
CHI Meng-yu,QIAN Heng-wei,ZHAO Ying,ZHAO Yan-xiang,HUANG Jin-guang.The FgCYP51B Y137H mutation is important for conidiation and ascospore development in Fusarium graminearum[J].Acta Phytopathologica Sinica,2019,49(2):283-288.
Authors:CHI Meng-yu  QIAN Heng-wei  ZHAO Ying  ZHAO Yan-xiang  HUANG Jin-guang
Institution:College of Plant Health and Medicine, Qingdao Agricultural University/Key lab of Integrated Crop Pest Management of Shandong Province, Qingdao 266109, China
Abstract:Tyrosine 137 is one of key residues in selective binding of DMIs to FgCYP51B(Fusarium graminearum CYP51B), which consists of a drug binding active pocket and plays an important role in the interaction between CYP51 and DMIs. In this study, we investigated the FgCYP51B Y137H biological phenotypes on conidiation, female fertility, colony morphology, growth rate, and pathogenicity. We found that the Y137H mutation of FgCYP51B showed a significantly reduction on conidiation and influences on development of ascospores compared with the wild-type strain. However, colony morphology, growth rate, and pathogenicity of the Y137H mutation of FgCYP51B were consistent with that of the wild-type strain. These results suggest that the FgCYP51B Y137H mutation has influences on conidiation and development of ascospores, but is not associated with colony morphology, growth rate and pathogenicity.
Keywords:Fusarium graminearum  CYP51B  mutagenesis  biological phenotype  
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