| 去除效价的土霉素药渣亚慢性毒性试验 |
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| 引用本文： | 孙宏丽,刘智勤,徐红欣,杨宝柱,任国强.去除效价的土霉素药渣亚慢性毒性试验[J].中国畜牧兽医,2010,37(1):164-165. |
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| 作者姓名： | 孙宏丽 刘智勤 徐红欣 杨宝柱 任国强 |
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| 作者单位： | (1.河北大学药学院， 保定 071002； 2.河北大学物理科学与技术学院， 保定 071002) |
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| 基金项目： | 河北省科技厅项目(06215617) |
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| 摘 要： | 用小鼠对去除效价的土霉素药渣进行亚慢性毒性试验,探讨在处理土霉素药渣过程中是否产生有毒物质。结果表明,饲喂处理后药渣的小鼠与饲喂原药渣的小鼠各脏器系数没有显著差异(P0.05),证明经过处理的药渣不仅与原药渣的各项指标相同,而且使残留效价大幅度降低。
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| 关 键 词： | 土霉素药渣 毒性 脏器系数 |
Subchronic Toxic Experiment of oxytetracycline Herb Residues Removed the Titer |
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| SUN Hong-li,LIU Zhi-qin,XU Hong-xin,YANG Bao-zhu,REN Guo-qiang.Subchronic Toxic Experiment of oxytetracycline Herb Residues Removed the Titer[J].China Animal Husbandry & Veterinary Medicine,2010,37(1):164-165. |
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| Authors: | SUN Hong-li LIU Zhi-qin XU Hong-xin YANG Bao-zhu REN Guo-qiang |
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| Institution: | (1.College of Pharmaceutical Science, Hebei University, Baoding 071002, China;2.College of Physics Science and Technology, Hebei University, Baoding 071002, China) |
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| Abstract: | The subchronic toxic of oxytetracycline removed the titer was tested by feeding mouse.Whether toxic substance is produced in the process of treating the oxytetracycline herb residues was studied.The results showed that the organ coefficient of mouse fed the worked herb residue was similar to the mouse fed the unworked herb residue(P>0.05).The indexes of worked herb residue are identical with that of unworked herb residue and it decreases the residues titer greatly. |
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| Keywords: | oxytetracycline herb residues toxic organ coefficient |
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