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Phosphonic analogues of morphactins. Part III: Peptides containing p-terminal 9-aminofluoren-9-ylphosphonic acid
Authors:Barbara Lejczak  Pawel Kafarski  Roman Gancarz  Elzbieta Jaskulska  Przemyslaw Mastalerz  Jan Sylwester Wieczorek  Marta Krl
Institution:Barbara Lejczak,Pawel Kafarski,Roman Gancarz,Elzbieta Jaskulska,Przemyslaw Mastalerz,Jan Sylwester Wieczorek,Marta Król
Abstract:Peptides of 9-aminofluoren-9-ylphosphonic or 1-aminocyclohexylphosphonic acids were synthesised and found to have typical morphactin activity when tested on Lepidium sativum and Triticum vulgare. The observed effects included root elongation with simultaneous stem shortening. The results obtained indicate that these phosphonic acid derivatives of cyclohexylamine and fluoren-9-ylamine may have a similar mechanism of action.
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