| 禽致病性大肠埃希菌黏附素研究进展 |
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| 引用本文： | 魏宽翠,夏玉龙,马兴树.禽致病性大肠埃希菌黏附素研究进展[J].动物医学进展,2012(3):105-109. |
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| 作者姓名： | 魏宽翠 夏玉龙 马兴树 |
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| 作者单位： | 河北工程大学农学院分子生物学实验室 |
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| 摘 要： | 黏附素是具有黏附宿主细胞能力的细菌表面结构的统称,是直接介导细菌对宿主细胞黏附的物质,故又称定居因子(colonization factor)。在禽致病性大肠埃希菌侵袭宿主组织并引起宿主发病的过程中,黏附是病原菌接触和感染细胞的第一步,因此,黏附素黏附宿主上皮细胞并使宿主致病的作用机理引起了研究者的广泛关注。论文通过对禽致病性大肠埃希菌黏附素的组成成分、黏附机制、种类、分子生物学特性以及相应的黏附素受体等进行相关综述,为研究禽大肠杆菌病的发病机理及对该病进行免疫预防提供理论依据。
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| 关 键 词： | 禽致病性大肠埃希菌 黏附素 基因 受体 |
Progress on Adhesin of Avian Pathogenic Escherichia coli |
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| WEI Kuan-cui,XIA Yu-long,MA Xing-shu.Progress on Adhesin of Avian Pathogenic Escherichia coli[J].Progress In Veterinary Medicine,2012(3):105-109. |
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| Authors: | WEI Kuan-cui XIA Yu-long MA Xing-shu |
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| Institution: | (Laboratory of Molecular Biology,Agricultural College,Hebei University of Engineering,Handan,Hebei,056021,China) |
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| Abstract: | Adhesin is a kind of bacterial surface components which directly involves the adhesion of bacteria and host cells,so it is called colonization factor.When they invade host tissue and cause host disease,adhesion is the first step to contact and infect the host epithelial cells,and then the pathogenic roles of adhesin attracted researchers’ wide attention in the avian pathogenic E.coli.Here,adhesin composition,adhesive mechanism,molecular biological characteristics and the corresponding adhesion receptors of avian pathogenic E.coli’s adhesin were reviewed,which would provide the theory to studying pathogenesis and immunoprophylaxis of colibacillosis. |
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| Keywords: | avian pathogenic E coli adhesin gene receptor |
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