| 外源寡糖对奶山羊免疫机能的影响 |
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| 引用本文： | 肖宇,程明,汪文鑫,王建华,张孝凯,祁茹,褚永康,李春蕾,林英庭.外源寡糖对奶山羊免疫机能的影响[J].兽医大学学报,2012(10):1516-1520. |
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| 作者姓名： | 肖宇 程明 汪文鑫 王建华 张孝凯 祁茹 褚永康 李春蕾 林英庭 |
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| 作者单位： | [1]青岛农业大学动物科技学院,山东青岛266109 [2]青岛市畜牧兽医研究所,山东青岛266100 [3]烟台市动物疫病预防与控制中心,山东烟台264003 |
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| 基金项目： | 山东省自然科学基金资助项目（ZR2009DM021）; 青岛市应用基础研究资助项目（11-2-4-5-（1）-jch） |
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| 摘 要： | 选用体况良好、年龄相近、体质量（32.80±2.45）kg、装有永久性瘤胃瘘管的崂山奶山羊6只,采用分期分组试验设计,分别饲喂添加1%（以有效含量计）甘露寡糖（MOS）、半乳甘露寡糖（GMOS）、果寡糖（FOS）、寡木糖（XOS）和异麦芽寡糖（IMO）的试验日粮,另设不添加寡糖的对照组。试验共分为4期,每期35d,其中预试期14d,正试期21d。结果表明：1）21d时,FOS组的血清碱性磷酸酶（AKP）含量显著升高（P〈0.05）,GMOS组的血清AKP、溶菌酶含量显著升高（P〈0.05）。2）21d时,FOS组、MOS组和GMOS组的血清免疫球蛋白A含量显著或极显著升高（P〈0.05或P〈0.01）;7、21d时,FOS组的血清免疫球蛋白G、M含量显著或极显著升高（P〈0.05或P〈0.01）;14、21d时,GMOS组的血清免疫球蛋白G、M含量显著或极显著升高（P〈0.05或P〈0.01）;7、14d时,MOS组的血清免疫球蛋白M含量极显著升高（P〈0.01）。3）7d时,FOS组血清白细胞介素-2、4、6含量显著或极显著升高（P〈0.05或P〈0.01）;7、21d时,GMOS组血清白细胞介素-2、6含量显著升高（P〈0.05）;14d时,FOS组和GMOS组血清白细胞介素-4含量显著升高（P〈0.05）。试验结果表明,不同外源寡糖对奶山羊有较好的免疫调节作用,其中,添加FOS和GMOS效果最好。
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| 关 键 词： | 寡糖 奶山羊 碱性磷酸酶 溶菌酶 免疫球蛋白 白细胞介素 |
Effect of different oligosaccharides in diet on the immune function of dairy goats |
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| Authors: | XIAO Yu CHENG Ming WANG Wen-xin WANG Jian-hua ZHANG Xiao-kai QI Ru CHU Yong-kang LI Chun-lei LIN Ying-ting |
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| Institution: | 1.College of Animal Science and Veterinary Medicine,Qingdao Agricultural University,Qingdao,Shandong 266109,China;2.Institute of Animal Husbandry and Veterinary Medicine of Qingdao,Qingdao,Shandong 266100,China;3.Animal Blight Prevention and Control Center of Yantai,Yantai,Shandong 264003,China) |
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| Abstract: | Effects of different oligosaccharides on the immune function of dairy goats were studied in this experiment.Six dairy goats with an average weight（32.80±2.45） kg,fitted with ruminal cannulas,were used by a staging and grouping experimental design.The test groups were fed on the diet on 1% of MOS,GMOS,FOS,XOS and IMO,respectively.The control group was fed on basal diet without oligosaccharides.The trial lasted for 4 stages of 35 days each,including preliminary trial period 14 days and formal trial period 21 days.The results showed that,compared with the control group,1） at 21 d,the serum concentration of AKP in FOS group was significantly increased（P0.05）,AKP and LSZ in GMOS group were significantly increased（P0.05）.2）IgA in FOS,MOS,GMOS groups were significantly increased（P0.05 or P0.01）;at 7 d and 21 d,IgG and IgM in FOS group were significantly increased（P0.05 or P0.01）;at 14 d and 21 d,IgG and IgM in GMOS group were significantly increased（P0.05 or P0.01）;at 7 d and 14 d,IgM in MOS group was significantly increased（P0.01）.3）at 7 d,IL-2,IL-4 and IL-6 in FOS group were significantly increased（P0.05 or P0.01）;at 7 d and 21 d,IL-2 and IL-6 in GMOS group were significantly increased（P0.05）;at 14 d,IL-4 in FOS and GMOS groups were significantly increased（P0.05）.In conclusion,different oligosaccharides can enhance immune function of dairy goats,and GMOS and FOS are consider to be the best supplementation. |
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| Keywords: | oligosaccharide dairy goat alkaline phosphatase lysozyme immunoglobulin interleukin |
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