|
|||||
|
|
Experimental studies of chronic pneumonia of sheep |
|
| Authors: | JS Gilmour GE Jones AG Rae |
| Institution: | Animal Diseases Research Association, Moredun Institute, 408 Gilmerton Road, Edinburgh EH 17 7JH, U.K. |
| Abstract: | Strains of Mycoplasma ovipneumoniae and Pasteurella haemolytica isolated from sheep affected with chronic pneumonia were inoculated by endobronchial route to conventionally-reared and SPF (Specific Pathogen-Free) lambs. Changes resembling those of the naturally-occurring disease were produced in most lambs given the organisms in combination and in some given M. ovipneumoniae alone. Similar but less extensive changes were seen in SPF lambs and fewer animals were affected. Different strains of M. ovipneumoniae did not affect the extent of changes produced in SPF lambs. M. ovipneumoniae became established in the lungs of both types of sheep; P. haemolytica did so less readily. It was concluded that chronic pneumonia may be reproduced in conventional animals by combined inoculation of M. ovipneumoniae and P. haemolytica. Age and status of immunity to mycoplasmas may account for the different responses of conventional and SPF lambs. |
| Keywords: | Sheep chronic pneumonia mycoplasmas Pasteurellae SPF lambsAuthor Keywords: Mouton pneumonie chronique mycoplasme Pasteurella agneaux SPF |
| 本文献已被 ScienceDirect 等数据库收录！ | |