| 沙门氏菌对六种氟喹诺酮类药物的敏感性试验 |
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| 引用本文： | 魏秀丽,陈杖榴.沙门氏菌对六种氟喹诺酮类药物的敏感性试验[J].中国兽药杂志,2005,39(9):4-8. |
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| 作者姓名： | 魏秀丽 陈杖榴 |
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| 作者单位： | 1. 华南农业大学兽医学院广东省兽药研制与安全评价重点实验室,广东,广州,510642;山东省兽药监察所,山东,济南,250022
2. 华南农业大学兽医学院广东省兽药研制与安全评价重点实验室,广东,广州,510642 |
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| 摘 要： | 对鸡源、猪源、人源、食品源的沙门氏菌进行了鉴定,对敏感菌株进行了耐药性诱导;并用琼脂平板二倍稀释法,测定了6种氟喹诺酮类药物对临床分离和体外诱导的68株沙门氏菌的MIC,结果表明临床沙门氏菌对环丙沙星的耐药率达61.8%(37/60),而且6种氟喹诺酮类药物之间的交叉耐药现象非常严重.
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| 关 键 词： | 氟喹诺酮类 沙门氏菌 耐药性 |
| 文章编号： | 1002-1280（2005）09-0004-05 |
| 收稿时间： | 2005-04-06 |
| 修稿时间： | 2005年4月6日 |
Studies on the minimum inhibitory concentration of six kinds of fluoroquinolones to Salmonella |
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| WEI Xiu-li,CHEN Zhang-liu.Studies on the minimum inhibitory concentration of six kinds of fluoroquinolones to Salmonella[J].Chinese Journal of Veterinary Drug,2005,39(9):4-8. |
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| Authors: | WEI Xiu-li CHEN Zhang-liu |
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| Abstract: | Normal biochemical reactions for 68 strains isolated from animals and human were determined.The (results) showed that majority of isolates were Salmonella according to bio-chemical reactions.High- and low-lever (resistance) of Salmonella to ciprofloxacin were obtained with serial passage in MH broth containing subinhibitory concentration of indicating ciprofloxacin or enrofloxacin. At the same time, the minimum inhibitory concentration (MIC) of six kinds of fluoroquinolones (FQs) to Salmonella of isolates were determined by agar dilution, 23 strains susceptible to ciprofloxacin and other 37 strains resistant to ciprofloxacin were screened out. |
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| Keywords: | fluoroquinolones(FQs) Salmonella resistance |
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