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Hereditary renal disease in a mutant strain of rats |
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| Authors: | B B Lozzio A I Chernoff E R Machado C B Lozzio |
| Abstract: | Disease of the kidney developed in breeding stock of Gunn rats. The renal lesion is the result of a new mutation. The genetic defect is inherited as an autosomal dominant trait and is apparently lethal in the homozygous condition. The abnormality manifests itself as a congenital hydronephrosis with related cystic changes in the kidney. |
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