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| 鹿胎盘生物活性多肽的制备及其药理作用研究 | |
| 引用本文： | 巴达马其其格,武晓东,侯霞,郑彬,武文华,李秀娟.鹿胎盘生物活性多肽的制备及其药理作用研究[J].内蒙古农业大学学报(自然科学版),2008,29(3). |
| 作者姓名： | 巴达马其其格 武晓东 侯霞 郑彬 武文华 李秀娟 |
| 作者单位： | 1. 内蒙古农业大学生态环境学院,呼和浩特,010019 2. 内蒙古大圣生物技术有限责任公司,包头,014060 3. 鄂尔多斯市水土保持淤地坝工程项目办公室,鄂尔多斯,017000 |
| 基金项目： | 国家自然基金(30760044); 内蒙古自然基金(200508010511) |
| 摘 要： | 采用低温酶解法制备鹿胎盘生物活性多肽,通过正交试验确定了其水解最佳条件,并将上述提取液进行超滤,得到分子量在3 000道尔顿以下的混合肽,通过混合肽主要成分的分离、小鼠灌肠实验、细胞培养实验,研究其药理作用,结果表明,鹿胎盘生物活性多肽具有镇静作用,促进神经细胞和人皮肤细胞生长作用,具有很好的临床应用及美容保健开发价值。 |
| 关 键 词： | 鹿胎盘生物活性多肽 低温酶解法 药理作用 |
DEER PLACENTA BIOLOGICAL ACTIVITY MULTI-PEPTIDE PREPARATION AND PHARMACOLOGICAL ACTION RESEARCH |
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| Badamaqiqige,WU Xiao-dong,HOU Xia,ZHENG Bin,WU Wen-hua,LI Xiu-juan.DEER PLACENTA BIOLOGICAL ACTIVITY MULTI-PEPTIDE PREPARATION AND PHARMACOLOGICAL ACTION RESEARCH[J].Journal of Inner Mongolia Agricultural University(Natural Science Edition),2008,29(3). | |
| Authors: | Badamaqiqige WU Xiao-dong HOU Xia ZHENG Bin WU Wen-hua LI Xiu-juan |
| Abstract: | The deer placenta biologic activity multi-peptides had been prepared by the low temperature enzymolysis method,and its extraction optimum condition has determined through the orthogonal test.The deer placenta extracts had been ultra filtered,than obtains the mix peptide that its molecular weight less than 3000 Dalton.Its pharmacological action had been studied through mix peptide principal constituent separation,experiment that irrigate the placenta extracts in mouse stomach,cell nurture experiment.The resu... |
| Keywords: | Deer placenta biologic activity multi-peptides low temperature enzymolysis method pharmacological action |
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