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| 沙棘籽油对牛的皮肤伤口愈合疗效的研究 | |
| 引用本文： | A.C.Varshney,S.P.Tyagi,Rajesh Rana,郭红艳,温秀凤.沙棘籽油对牛的皮肤伤口愈合疗效的研究[J].国际沙棘研究与开发,2008,6(1):30-35. |
| 作者姓名： | A.C.Varshney S.P.Tyagi Rajesh Rana 郭红艳 温秀凤 |
| 作者单位： | 1. 手术和放射学系,动物科学学院兽医系,CSKHPKV,Palampur,H.P.,India 2. 北京林业大学水土保持学院,北京,100083 3. 水利部沙棘开发管理中心,北京,100038 |
| 摘 要： | 本研究旨在通过比较沙棘籽油（Hippophae rhamnoides）和防腐软膏（5％碘伏）、草本软膏（印度草药研究与供应有限公司）及一种刺激性温和的基础药膏（液体石蜡），来研究沙棘籽油对牛的皮肤伤口愈合效果。这个实验是将12头雄性牛犊分为4组，6头牛都有皮肤伤口，3头胸背部脊椎区的两边都用当地的镇痛药。伤口分别用液体石蜡、5％的碘伏软膏、沙棘籽油（沙棘油）及草本软膏处理28d，并分为Ⅰ、Ⅱ、Ⅲ、Ⅳ四组。不同处理的功效是建立在对经过0d、3d、7d、10d、14d和28d的不同临床血液参数的研究基础之上的。在研究中，所有组的心脏、呼吸率和血液学的各种参数及肛温都维持在正常的生理极限内。沙棘油和草本软膏对伤口处理的临床研究中发现，在伤口愈合的初期，伤口保持了一定的干燥度，并且抑制了炎症初期伤口的恶化。不同的组之间，在持续28d的实验中，用草本软膏和沙棘油做处理的组中伤口的愈合率最高。这些组的伤口试验同时还表现出早治疗，早治愈的特征。但是，在草本软膏和沙棘油处理组中，草本软膏组处理的伤口的整体愈合能力还是略优于沙棘油的疗效。 |
| 关 键 词： | 沙棘 牛的伤口愈合 皮肤 |
| 文章编号： | 1672-4683(2008)01-0030-06 |
| 修稿时间： | 2005年7月15日 |
Therapeutic Efficacy of Seabuckthorn and Dermanol in the Healing of Cutaneous Wounds in Bovine |
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| Authors: | ACVarshney SPTyagi Rajesh Rana Guo Hongyan Wen Xiufeng |
| Institution: | A.C. Varshney, S.P. Tyagi ,Rajesh Rana( Department of Surgery and Radiology, College of Veterinary and Animal Sciences CSKHPKV, Palampur, H.P., India) |
| Abstract: | The present study was designed to evaluate the therapeutic efficacy of seabuckthorn （Hippophae rhamnoides） seed oil in the healing of aseptic full thickness cutaneous wounds in calves and compared with antiseptic ointment （5% povidone--iodine）, a commercially available herbal ointment （Dermanol, Indian Herbs Research and Supply Company Ltd. , Saharanpur, India） and a bland ointment base （liquid paraffin） . The study was conducted on 12 male calves divided into 4 equal groups. In each animal, six full thickness equidimentional cutaneous wounds, 3 on either side of vertebral column at dorsal thoracolumbar region were created under local analgesia. The wounds were dressed with liquid paraffin, 5% povidone--iodine ointment, seabuckthorn （SBT） seed oil and Dermanol in group Ⅰ , Ⅱ ,Ⅲand Ⅳ respectively till 28 days. The efficacy of different treatments was monitored on the basis of different clinical and haematological parameters at 0, 3, 7, 10, 14, 21, and 28 days. The cardiac and respiration rates, rectal temperature and various haematological parameters remained within normal physiological limit in all groups during the study. Clinically the SBT and Dermanol treated wounds remained relatively drier and exhibited less pronounced inflammatory reactions during early stage of wound healing. The percent wound contraction was greater in Dermanol and SBT treated groups at different intervals till 28 days. The wounds of these groups also exhibited early formation of firm scab and its earlier shedding. However, in between Dermanol and SBT treated groups, the overall wound healing was comparatively slightly better in Dermanol treated wounds. |
| Keywords: | seabuckthorn wound healing bovine dermanol |
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