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辛夷油的药理学研究
引用本文:王文魁,沈映君,齐云,孙晋红,田永庆.辛夷油的药理学研究[J].畜牧兽医学报,2002,33(2):145-147.
作者姓名:王文魁  沈映君  齐云  孙晋红  田永庆
作者单位:1. 山西农业大学动科院,太谷,030801
2. 成都中医药大学药学院
3. 山西省太谷县畜牧局
摘    要:向大白鼠胸腔注入角叉菜胶诱发胸膜炎,8h后处死动物,测定其胸腔渗出液中白细胞数、蛋白质及前列腺素E2(PGE2)的含量,体内白细胞介素1(IL-1)和肿瘤坏死因子(TNF)的含量。结果显示,事先灌服辛夷油的试验组动物,其胸腔渗出液中白细胞数、蛋白质和PGE2的含量均显著小于模型对照组;IL-1和TNF的含量也明显小于模型组,说明辛夷油能抑制炎症介质的产生,具有抗炎效应。

关 键 词:辛夷  挥发油  药理学  中药
文章编号:0366-6964(2002)02-0145-03

Pharmacological Study of the Volatile Oil of Flos Magnoliae L.
WANG Wen-kui,SHEN Ying-jun,QI Yun,SUN Jin-hong,TIAN Yong-qing.Pharmacological Study of the Volatile Oil of Flos Magnoliae L.[J].Acta Veterinaria et Zootechnica Sinica,2002,33(2):145-147.
Authors:WANG Wen-kui  SHEN Ying-jun  QI Yun  SUN Jin-hong  TIAN Yong-qing
Abstract:1% Carrageenan was injected into rats' thoracic cavity so that acute pleurisy occurred to the rats. Eight hours later, all rats were killed, and the following physiochemical indexes were measured: leucocyte count, the content of protein,prostaglandin E2(PGE2) and tumuor necrosis factor(TNF) in the pleural exudate.inter-leukin 1(IL- 1) in abdominal cavity. The results showed that the protein,leucocyte count,PGE2,TNF and IL-1 of the treatment rats that were given VOMbP( volatile oil of Magnolia biondii Pamp. ) before were less than those of the model control rats which weren't given VOMbP. It is inferred that VOMbP could inhibit the production of inflammatory mediators and effect anti-inflammatory action.
Keywords:Flos Magnoliae L  Volatile oil  Pharmacology
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