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犬基底细胞癌的病理组织学观察
引用本文:潘俊斌,刘博奇,林凯,于博.犬基底细胞癌的病理组织学观察[J].畜牧兽医杂志,2012(3):20-22.
作者姓名:潘俊斌  刘博奇  林凯  于博
作者单位:华南农业大学;广州中医药大学科技产业园有限公司 新南方药物安全性评价中心
摘    要:基底细胞癌(basal cell carcinoma,BCC)是一种常见的低度皮肤恶性肿瘤,又名基底细胞上皮癌、基底细胞癌和侵蚀性溃疡。本文主要探讨皮肤基底细胞癌的临床病理诊断和鉴别诊断要点,为提高基底细胞癌的诊治水平提供依据。通过病理组织学观察,皮肤破溃、出血,肿瘤细胞成团块状增生,由结缔组织分割为不规则小叶状。细胞呈梭形、多边形及近圆形;细胞核圆形,核膜清晰,有一明显核仁,有一定异形性,偶见分裂相,作为确诊基底细胞肉瘤的主要依据,并对疾病的处理和治疗方法进行了归纳和总结。

关 键 词:基底细胞癌  肿瘤  病理组织学  治疗方法

Histopathological Observation of Dog Basal Cell Carcinoma
PAN Jun-bin,LIU Bo-qi,LIN Kai,YU Bo.Histopathological Observation of Dog Basal Cell Carcinoma[J].Journal of Animal Science and Veterinary Medicine,2012(3):20-22.
Authors:PAN Jun-bin  LIU Bo-qi  LIN Kai  YU Bo
Institution:1(1.South China Agricultural University,Guangzhou Guangdong 510642,China; 2.New Southern Drug Safty Evaluation Center,Sci-Tech Industrial Park Co.Ltd.,Guangzhou University of Chinese Medicine)
Abstract:Basal cell carcinoma(BCC) is a common low-degree skin malignant tumor,which is also named erosion ulcers.This paper discusses the main points of clinical pathology diagnosis and differential diagnosis of this carcinoma,in order to provide the basis to improve the level of diagnosis and treatment of basal cell carcinoma.The pathological change includes skin ulcer,hemorrage,massive proliferation of tumor tissues which is divided into irregular lobules.And the cells of tumor reveal spindle and polygons and nearly round,the nucleuses are round and had an obvious karyotheca.There is always one distinct nucleolus which may manifest atypia,and mitotic figure can be discovered sometimes.To sum up,all these characters can be used as the main basis of the BCC,and this diagnosis may provide the help to the future therapy.
Keywords:basal cell carcinoma  tumor  histopathology  therapy
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