| 腹腔镜下保守手术治疗不同类型子宫内膜异位症并发不孕患者疗效的对比研究 |
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| 作者姓名： | 徐红 王菲 |
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| 作者单位： | 中国人民解放军海军安庆医院妇科,安徽 安庆 246000,中国人民解放军海军安庆医院妇科,安徽 安庆 246000 |
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| 摘 要： | 目的 探讨腹腔镜下保守手术治疗不同类型子宫内膜异位症(简称内异症)合并不孕患者的疗效。方法 选择因内异症合并不孕行腹腔镜保守性手术治疗的145例患者,术后随访1～5年,观察自然妊娠结局及复发情况。结果 深部浸润组术后GnRH-a用药情况分别与卵巢组和腹膜组比较,均差异有统计学意义(均P<0.05),而卵巢组与腹膜组比较,差异无统计学意义(P>0.05)；三组累积妊娠率分别比较,均差异无统计学意义(P>0.05)；深部浸润组、卵巢组、腹膜组三组患者术后妊娠距手术的间隔时间分别为(37.4±1.5)、(9.3±2.3)、(6.5±1.9)个月,深部浸润组与卵巢组及腹膜组比较,均延长(P<0.05)；三组复发率比较,差异无统计学意义但P值较小(P=0.052)。结论 深部浸润型内异症患者手术后平均妊娠时间延长,但累积妊娠率与卵巢型和腹膜型内异症相似。
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| 关 键 词： | 子宫内膜异位症 腹腔镜检查 不孕 手术 |
| 收稿时间： | 2016/10/8 0:00:00 |
| 修稿时间： | 2016/11/26 0:00:00 |
Clinical effect on women with different types of endometriosis related infertility treated by conservative laparoscopic surgery |
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| Authors: | XU Hong and WANG Fei |
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| Abstract: | Objective To study pregnancy outcome and recurrence in patients with different type of endometriosis related infertility treated by conservative laparoscopic surgery. Methods 145 patients with endometriosis related infertility undergoing conservative laparoscopic surgery in Navy Anqing Hospital were collected and randomly assigned into deepinfiltratingendometriosisgroup,ovarianendometriosis group andperitoneal endometriosis group.During 1- to 5-year follow-up after surgery,natural pregnancy outcome and recurrence of endometriosis were studied. Results Compared with ovarian and peritoneal endometriosis group,the postoperative use of medication GnRH-ain deep infiltrating endometriosis group had significant difference (both P<0.05),whilethere was no statistically significant difference between ovarian and peritoneal endometriosis group (P> 0.05).There were no statistical differencein the accumulated pregnancy rateamong three groups (P>0.05).The mean intervals between pregnancy and surgery were (37.4±1.5) months in deep infiltrating endometriosis group,(9.3±2.3) in ovarian endometriosis group and (6.5±1.9) months in peritoneal endometriosis group.The mean interval in deepinfiltrating endometriosis was significantly longer than that in peritoneal endometriosis group and ovarian endometriosis group(P<0.05).The difference was not statistically significant in recurrence rate,but the Pvalue was smaller (P=0.052). Conclusions The interval between pregnancy and surgery was significantly longer in patients with deep infiltrating endometriosis when compared with othergroups.However,there was no difference among these three groups in accumulated pregnancy rate. |
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