Productive performance of the dairy cattle Girolando breed mediated by the fat-related genes DGAT1 and LEP and their polymorphisms |
| |
| Institution: | 1. Lebedev Physical Institute (LPI) of Russian Academy of Sciences, Samara Branch, 443011 Samara, Russia;2. Institute of Structural Macrokinetics and Materials Science (ISMAN), RAS, Chernogolovka 142432, Russia;1. Research Center, Education and Extension in Livestock (NUPEEC), College of Veterinary, Federal University of Pelotas, Pelotas, RS, Brazil;2. Department of Nutrition, College of Nutrition, Federal University of Pelotas, Pelotas, RS, Brazil;1. Laboratory of Reproductive Biology, University Hospital of Copenhagen, Copenhagen OE, Denmark;2. ORIGIO A/S, Maaloev, Denmark;3. Centre for Clinical Proteomics, Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark;4. Department of Veterinary Reproduction and Obstetrics, University of Copenhagen, Frederiksberg C, Denmark;5. Department of Clinical Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg C, Denmark;2. Dairy Science Department, Virginia Polytechnic Institute and State University, Blacksburg 24061;3. Embrapa Gado de Leite, Juiz de Fora, Minas Gerais, Brazil 36038–330;1. Departamento de Zootecnia, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, MG 31270-901, Brazil;2. CSIRO Agriculture & Food, Brisbane, QLD 4067, Australia;3. Embrapa Gado de Leite, Juiz de Fora, MG, 36038-330, Brazil;4. Embrapa Pecuária Sul, Bagé, RS, 96401-970, Brazil |
| |
| Abstract: | Candidate genes have been associated with milk production in bovines, such as the diacylglycerol O-acyltransferase 1 (DGAT1) and leptin (LEP); however, they have not been simultaneously investigated nor have been evaluated in the Brazilian Girolando breed (Gir × Holstein, backcrossed to Holstein). Our aim was to determine the influence of fat-related genes, DGAT1 and LEP, and their polymorphisms on performance traits of milk production in the Girolando breed. Results indicated that the K allele of the DGAT1 gene showed a significant association with total and average daily milk production with additive effect. The LEP gene showed that the A allele and its homozygote are highly prevalent and almost fixed in this population and may have been favorably selected during backcrossing for the origin of this breed. The important impact of the K allele of the DGAT1 gene on milk production corroborates the initiative of performing marker-assisted selections with this gene in breeding programs of the Girolando breed. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
