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北极微生物的分离及抗菌抗肿瘤活性筛选
引用本文:那广水,周传光,叶亮,孙茜,姚子伟,李红霞,奚涛.北极微生物的分离及抗菌抗肿瘤活性筛选[J].水产科学,2008,27(8).
作者姓名:那广水  周传光  叶亮  孙茜  姚子伟  李红霞  奚涛
作者单位:1. 中国药科大学,生命科学与技术学院,江苏,南京,210009;国家海洋环境监测中心,辽宁,大连,116023
2. 国家海洋环境监测中心,辽宁,大连,116023
3. 中国药科大学,生命科学与技术学院,江苏,南京,210009
基金项目:国家极地科学战略研究基金
摘    要:采用多种培养基对北极地区(海洋沉积物、湖泊沉积物及土壤)微生物进行分离,并采用琼脂平板打孔法和MTT法进行了抗菌、抗肿瘤活性菌株的筛选.共分离极地微生物151株,筛选结果显示,12.4%的菌株有抗菌活性,6.2%菌株有抗肿瘤活性,其中3株同时具有抗菌、抗肿瘤活性,表明极地有良好的微生物药用资源.

关 键 词:北极微生物  抗菌  抗肿瘤  筛选

Isolation of Arctic Microorganisms and Screening of Antimicrobial and Antitumor Activity
NA Guang-shui,ZHOU Chuan-guang,YE Liang,SUN Qian,YAO Zi-wei,LI Hong-xia,XI Tao.Isolation of Arctic Microorganisms and Screening of Antimicrobial and Antitumor Activity[J].Fisheries Science,2008,27(8).
Authors:NA Guang-shui  ZHOU Chuan-guang  YE Liang  SUN Qian  YAO Zi-wei  LI Hong-xia  XI Tao
Abstract:There were some samples collected from the Arctic soil and marine sediment for isolation of microorganisms and screening of their antimicrobial and antitumor bioactivity by agar plate diffusion method and MTT.The 151 stains were isolated from the samples,12.4% of the Arctic microorganisms showed antimicrobial activity,6.2% showed antitumor activity and 3 strains showed both of them.These results showed that the Arctic had good potential microorganisms resource in bioactive metabolites.
Keywords:arctic microorganism  antimicrobial activity  antitumor activity  screening
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