| 奶牛激素相关的乳腺MicroRNA研究进展 |
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| 引用本文： | 刘子豪,蒋林树,南雪梅,熊本海.奶牛激素相关的乳腺MicroRNA研究进展[J].动物营养学报,2021,33(1). |
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| 作者姓名： | 刘子豪 蒋林树 南雪梅 熊本海 |
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| 作者单位： | 中国农业科学院北京畜牧兽医研究所,动物营养学国家重点实验室,北京 100193;北京农学院动物科学技术学院,北京 102206 |
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| 基金项目： | 国家“十三五”国家重点研发计划(2017YFD0701604,2016YFD0700205,2016YFD0700201)。 |
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| 摘 要： | MicroRNA(miRNA)是一种非编码RNA,在调节细胞增殖、分化和凋亡的过程中起重要作用。研究表明,激素通过单独或相互作用完成对奶牛乳腺发育和泌乳进程的调控。本文从激素对奶牛乳腺miRNA表达谱影响及miRNA通过激素受体及其下游通路调控乳腺功能2个方面,综述了激素与相关miRNA的研究现状,以期助力于乳腺生物学的发展及奶产品质量的提高。
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| 关 键 词： | 奶牛 激素 miRNA 乳腺发育 |
Research Progress of Mammary MicroRNA Related to Hormones in Dairy Cows |
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| LIU Zihao,JIANG Linshu,NAN Xuemei,XIONG Benhai.Research Progress of Mammary MicroRNA Related to Hormones in Dairy Cows[J].Acta Zoonutrimenta Sinica,2021,33(1). |
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| Authors: | LIU Zihao JIANG Linshu NAN Xuemei XIONG Benhai |
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| Institution: | (State key Laboratory of Animal Nutrition,Institute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing 100193,China;Beijing University of Agriculture,Beijing 102206,China) |
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| Abstract: | MicroRNA(miRNA)is a kind of non-coding RNA that plays an important role in regulating various cell processes,including replication,differentiation and apoptosis.The research has showed that hormones can regulate the development and lactation of the mammary gland of dairy cows individually or interactively.This article reviewed the research progress of hormones related miRNA from two aspects:the effects of hormones on the expression profile of miRNA in dairy cow mammary and the regulation of mammary functions by the miRNA through hormone receptors and their downstream pathways,in order to help the development of mammary biology and the improvement of milk product quality. |
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| Keywords: | dairy cow hormones miRNA mammary gland |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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