Electrospinning of silk nanofibers. I. An investigation of nanofiber morphology and process optimization using response surface methodology |
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| Authors: | Nasim Amiraliyan Mahdi Nouri Mohammad Haghighat Kish |
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| Institution: | (1) Textile Department, Guilan University, Rasht, Iran;(2) Textile Department, AmirKabir University of Technology, Tehran, Iran |
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| Abstract: | Ultra fine fibers were electrospun from regenerated silk fibroin/formic acid solution. Effect of some process parameters on
the morphology, diameter and variation in fiber diameter of electrospun fibers were experimentally investigated. Scanning
electron microscope was used for the measurement of fiber diameter. Fibers with diameter ranging from 80 to 210 nm were collected
depending on the solution concentration and the applied voltages. Response surface methodology (RSM) was used to obtain a
quantitative relationship between selected electrospinning parameters and the average fiber diameters and its distribution.
It was shown that concentration of silk fibroin solution had a significant effect on the fiber diameter and the standard deviation
of the fiber diameter. Applied voltage had no significant effect on the fiber diameter and its standard deviation. |
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| Keywords: | Biopolymer Electron microscopy Morphology Protein Nanofiber Statistical analysis |
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