| 鸡腿菇转化桑叶发酵液的降血糖作用研究 |
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| 引用本文： | 钱静亚,张志才,黄达明,崔凤杰,郑惠华,陈惠.鸡腿菇转化桑叶发酵液的降血糖作用研究[J].中国食用菌,2012(4):46-50. |
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| 作者姓名： | 钱静亚 张志才 黄达明 崔凤杰 郑惠华 陈惠 |
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| 作者单位： | [1]江苏大学食品与生物工程学院,江苏镇江212013 [2]江苏安惠生物科技有限公司,江苏南通226009 |
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| 基金项目： | 江苏大学高级专业人才科研启动基金（项目编号：1283000268）、南通社会发展基金（编号：S2008004）. |
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| 摘 要： | 研究了鸡腿菇转化桑叶发酵液的降血糖作用,测定了糖尿病小鼠喂养鸡腿菇转化桑叶发酵液后血糖、血脂及肝脏、肾脏组织中的超氧化物岐化酶酶活等指标,并分析了发酵液中的成分。结果表明,鸡腿菇转化桑叶发酵液可以降低血清中血糖、果糖胺、甘油三酯、丙二醛含量,提高脏器中超氧化物岐化酶活性;同时,与未转化桑叶的发酵液相比,鸡腿菇转化桑叶发酵液中具有降血糖作用的黄酮和多酚含量显著增加高,进一步分离得到的4,5-二羟基,2-甲氧基-苯甲醛含量也显著提高。无论从功效还是发酵液成分变化都已说明鸡腿菇转化桑叶发酵液具有很好的降血糖作用,为药用真菌转化中药提高降血糖作用提供了参考。
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| 关 键 词： | 鸡腿菇 桑叶 生物转化 发酵液 降血糖 |
Hypoglycemic Effect of Coprinus comatus Broth Biotransformating Mulberry Leaves |
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| QIAN Jing-Ya,ZHANG Zhi-Cai,HUANG Da-Ming,CUI Feng-Jie,ZHENG Hui-Hua,CHEN Hui.Hypoglycemic Effect of Coprinus comatus Broth Biotransformating Mulberry Leaves[J].Edible Fungi of China,2012(4):46-50. |
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| Authors: | QIAN Jing-Ya ZHANG Zhi-Cai HUANG Da-Ming CUI Feng-Jie ZHENG Hui-Hua CHEN Hui |
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| Institution: | 1.College of Food and Biological Engineering, Jiangsu University, Zhenjiang, 212013, China; 2.Anhui-bioscience technological Co.Ltd, Nantong,226009) |
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| Abstract: | Hypoglycemic effect of Coprinus comatus broth biotransformating mulberry leaves was studied. The indicators of blood glucose, lipid and enzyme activitie of superoxide dismutase in liver and kidney were determined when the dia- betic mice were fed by C. comatus broth biotransformating mulberry leaves. The composition contents in C. comatus broth biotransformating mulberry leaves were also analyzedl The results showed that the levels of blood glucose, triglyceride, malond!aldehyde in serum were reduced, and enzyme activitie of superoxide dismutase in liver and kidney was improved. The contents of flavone and polyphenol in C. comatus broth biotransformating mulberry leaves were improved and 4,5- Dihydroxy-2-Methoxy-Benzaldehyd separated from broth were also improved. Therefore, C. comatus broth biotransfor- mating mulberry leaves.showed a significant hypoglycemic effect and the study provides a useful information on improving hypoglycemic activity of the herb through biotransformation of medicinal fungi. |
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| Keywords: | Coprinus comatus Mulberry leaves Biotransformation Fermentation broth Hypoglycemic effect |
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