| 磺胺-6-甲氧嘧啶在鸡体内代谢动力学的研究 |
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| 引用本文： | 胡祖禹,张福华,王天益,柳仲华,傅佑全.磺胺-6-甲氧嘧啶在鸡体内代谢动力学的研究[J].四川农业大学学报,1987(2). |
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| 作者姓名： | 胡祖禹 张福华 王天益 柳仲华 傅佑全 |
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| 作者单位： | 四川农业大学，四川农业大学，四川农业大学，四川农业大学，四川农业大学 |
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| 摘 要： | 用鸡十一只,其中八只静注,三只皮下注射。制菌磺钠的剂量为70mg/kg。用重氮化—偶合比色法(Annino法)显色,用72型分光光度计测定,波长为550nm。经测定主要动力学参数:半衰期为9.21小时;表观分布容积为0.60L/kg;零时血药浓度为25.80mg％;血药有效浓度维持时间为12.39小时。
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| 关 键 词： | 药物动力学(47UA) 鸡(49ME) 生物鉴定(45AA) 磺胺药 药物血清浓度 |
PHARMACOKINETICS OF SULFAMONOMETHOXINE IN HENS |
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| Hu Zuyu et al.PHARMACOKINETICS OF SULFAMONOMETHOXINE IN HENS[J].Journal of Sichuan Agricultural University,1987(2). |
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| Authors: | Hu Zuyu |
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| Abstract: | Pharmacokinetics of sulfamonomethoxine for injections were studied in healthy adult hens. A single dose(70mg/kg) of drug was administered as an intravenous bolus and blood samples were collected at precisely timed intervals. The samples were analyzed chemically Annino method. The main kinetic parameters of sulfamonomethoxine were determined. |
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| Keywords: | PHARMACOKINETICS DOMESTIC FOWL BIOASSAY SULFONAMIDES DRUG BLOOD CONCENTRATION |
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