Reference values of hematological and biochemical parameters for the world smallest microminipigs |
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Authors: | Kawaguchi Hiroaki Yamada Tomonobu Miura Naoki Takahashi Yoshihiro Yoshikawa Tsuyoshi Izumi Hiroyuki Kawarasaki Tatsuo Miyoshi Noriaki Tanimoto Akihide |
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Institution: | Laboratory of Veterinary Histopathology, Joint Faculty of Veterinary Medicine, Kagoshima University, 1-21-24 Korimoto, Kagoshima 890-0065, Japan. |
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Abstract: | In this study, we demonstrated growth curves and reference values for hematological and serum biochemical parameters of Microminipigs, the world smallest experimental minipigs. In both male and female animals, the body weights (BWs) at 3 and 6 months of age were <5 kg and <10 kg, respectively, and growth curve revealed almost plateau (approximately 20 kg BW) after 18 months of age. Major hematological and serum biochemical parameters showed no gender differences and the values were very similar to those in G?ttingen and Yukatan minipigs. The values obtained in this study can serve as fundamental reference, and thereby facilitate the use of Microminipig in life science research. |
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