| 口蹄疫新型疫苗研究进展 |
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| 引用本文： | 白婧,许崇波,张强,高凤山.口蹄疫新型疫苗研究进展[J].中国畜牧兽医,2009,36(11):126-129. |
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| 作者姓名： | 白婧 许崇波 张强 高凤山 |
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| 作者单位： | （1.大连大学生物工程学院， 大连 116622； 2.大连大学医学院， 大连 116622；3.中国农业科学院兰州兽医研究所， 兰州 730046） |
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| 摘 要： | 口蹄疫是由口蹄疫病毒感染引起的偶蹄动物共患的急性、热性、接触性传染病，接种疫苗是特异性预防口蹄疫的有效手段，口蹄疫疫苗主要有弱毒疫苗、灭活疫苗及新型疫苗。自20世纪80年代开始,基因工程亚单位疫苗、合成肽疫苗、病毒活载体疫苗、基因缺失疫苗、重组表位疫苗、核酸疫苗等新型疫苗研究日趋活跃，现对各类型疫苗的研究进展作一综述。
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| 关 键 词： | 口蹄疫 传统疫苗 新型疫苗 |
Progress on New Types of Foot-and-mouth Disease Vaccine |
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| BAI Jing,XU Chong-bo,ZHANG Qiang,GAO Feng-shan.Progress on New Types of Foot-and-mouth Disease Vaccine[J].China Animal Husbandry & Veterinary Medicine,2009,36(11):126-129. |
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| Authors: | BAI Jing XU Chong-bo ZHANG Qiang GAO Feng-shan |
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| Institution: | (1.College of Bioengineering, Dalian University, Dalian 116622, China; 2.College of Medicine, Dalian University, Dalian 116622, China； 3.Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzou 730046, China) |
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| Abstract: | Foot-and-mouth disease (FMD) is caused by foot-and-mouth disease virus and infect cloven-hoofed animals. It is suffering from acute, fever, sexually transmitted diseases contact. Vaccination is still an effective measure to prevent and control FMD. The main foot-and-mouth vaccines are attenuated vaccines, inactivated vaccines and new vaccines. Since the 1980s, genetic engineering subunit vaccines, synthetic peptide vaccines, vaccine vectors, gene deletion vaccines and recombinant vaccine epitopes, the DNA vaccine and other new types of vaccine research has become increasingly active. The progress of types of vaccine are reviewed. |
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| Keywords: | foot-and-mouth disease traditional vaccines new types of vaccine |
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