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Body conformation in Great Danes with and without clinical signs of cervical spondylomyelopathy
Institution:1. Leibniz-Institute for Farm Animal Biology (FBN), Institute for Genome Biology, Wilhelm-Stahl-Allee 2, Dummerstorf 18196, Germany;2. Clinic for Cattle, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, Hannover 30173, Germany;3. Department of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Bünteweg 9, Hannover 30559, Germany;4. Faculty of Agricultural and Environmental Sciences, University Rostock, Justus-von-Liebig-Weg, Rostock 18059, Germany;1. Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon Tharp St., Columbus, OH 43210, USA;2. School of Health and Rehabilitation Sciences, The Ohio State University, 453 West Tenth Ave., Columbus, OH 43210, USA;3. Center for Biostatistics, The Ohio State University, 601 Vernon Tharp St., Columbus, OH 43210, USA;1. Department of Veterinary Medicine, University of Sassari, Sassari, Italy;2. Department of Clinical Sciences of Companion Animals Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands;3. Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands;1. Department of Anatomy, Embryology and Animal Genetics, Veterinary Faculty, University of Zaragoza, Miguel Servet 177, Zaragoza 50013, Spain;2. Department of Animal Pathology, Veterinary Faculty, University of Zaragoza, Miguel Servet 177, Zaragoza 50013, Spain;1. Department of Small Animal Medicine and Surgery, University of Veterinary Medicine, Hannover, Germany;2. Department of Biometry, Epidemiology and Information Processing, University of Veterinary Medicine, Hannover, Germany
Abstract:It has been suggested that a combination of large head and long neck cause abnormal forces on the cervical vertebral column and are involved in the pathogenesis of cervical spondylomyelopathy (CSM) in Great Danes. The aim of this study was to compare the body conformation of 15 clinically normal and 15 CSM-affected Great Danes. There were no statistically significant differences between clinically normal and CSM-affected Great Danes in any body measurements. There were no significant associations between body conformation and the severity of neurological signs or cervical vertebral body dimensions determined by magnetic resonance imaging in CSM-affected Great Danes. The results of this study do not support the hypothesis that differences in body conformation related to head size, neck length, and body height and length, play a role in the pathogenesis of CSM in Great Danes.
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