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Hydrated nucleus pulposus herniation in seven dogs
Institution:1. Department of Veterinary Medicine, University of Sassari, Sassari, Italy;2. Department of Clinical Sciences of Companion Animals Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands;3. Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands;1. Clinical Science and Services, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK;2. Davies Veterinary Specialists, Manor Farm Business Park, Higham Gobion SG5 3HR, UK;1. Leibniz-Institute for Farm Animal Biology (FBN), Institute for Genome Biology, Wilhelm-Stahl-Allee 2, Dummerstorf 18196, Germany;2. Clinic for Cattle, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, Hannover 30173, Germany;3. Department of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Bünteweg 9, Hannover 30559, Germany;4. Faculty of Agricultural and Environmental Sciences, University Rostock, Justus-von-Liebig-Weg, Rostock 18059, Germany;1. Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon Tharp St., Columbus, OH 43210, USA;2. School of Health and Rehabilitation Sciences, The Ohio State University, 453 West Tenth Ave., Columbus, OH 43210, USA;3. Center for Biostatistics, The Ohio State University, 601 Vernon Tharp St., Columbus, OH 43210, USA;1. Clinical Science and Services, The Royal Veterinary College, University of London, Hatfield, UK;2. Department of Medicine and Clinical Biology of Small Animal, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium;1. Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, 601 Vernon TharP St., Columbus, OH 43210, USA;2. School of Health and Rehabilitation Sciences, The Ohio State University, 453 West Tenth Ave, Columbus, OH 43210, USA;3. Center for Biostatistics, The Ohio State University, 601 Vernon TharP St., Columbus, OH 43210, USA
Abstract:The clinical signs, magnetic resonance imaging (MRI) findings, treatment and follow-up in seven dogs with hydrated nucleus pulposus extrusion (HNPE) are reported. All dogs had tetraparesis or tetraplegia. T2-weighted MRI revealed extradural hyperintense homogeneous material compressing the cervical spinal cord. After conservative treatment (five dogs) or surgical decompression (two dogs), all dogs returned to ambulatory function within 1 month. Follow-up MRI in conservatively treated dogs revealed complete disappearance of the extruded material. Histopathological examination of surgical specimens confirmed that the retrieved material was extruded nucleus pulposus with evidence of early degeneration.
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