| 汉麻黄酮类成分研究进展 |
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| 引用本文： | 姜硕,万璐,许哲祥,闫佳佳,郑春英.汉麻黄酮类成分研究进展[J].中国农学通报,2021,37(17):120-128. |
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| 作者姓名： | 姜硕 万璐 许哲祥 闫佳佳 郑春英 |
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| 作者单位： | 1.黑龙江大学农业微生物技术教育部工程研究中心,哈尔滨 150500;2.黑龙江大学生命科学学院/黑龙江省普通高校微生物重点实验室,哈尔滨 150080 |
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| 基金项目： | 黑龙江省现代农业产业技术协同创新体系项目“麻类食品与药物研发协同创新项目”(YYM19STX-1) |
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| 摘 要： | 为了高效利用汉麻黄酮类成分及系统开展汉麻黄酮类化合物的研究,本文综述了汉麻黄酮类化合物的结构、合成途径、生物活性及分析方法。归纳总结出汉麻中共含有26种黄酮类化合物,其主要结构类型以黄酮和黄酮醇为主;此外,在黄酮类化合物经典合成途径的基础上,明确了2种特征性汉麻黄酮成分-大麻黄素A和大麻黄素B的生物合成途径;同时,也总结了汉麻黄酮类化合物具有抗肿瘤、神经保护、抗抑郁等生物活性,并针对其结构特点和活性作用,建立了汉麻黄酮类化合物高效、快速的分析方法为LC-MS等功效。上述归纳可为开展汉麻黄酮类化合物的研究及应用提供参考。
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| 关 键 词： | 汉麻 黄酮类化合物 结构 生物活性 合成途径 分析方法 |
| 收稿时间： | 2020-09-20 |
Research Progress on Flavonoids of Cannabis sativa L |
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| Jiang Shuo,Wan Lu,Xu Zhexiang,Yan Jiajia,Zheng Chunying.Research Progress on Flavonoids of Cannabis sativa L[J].Chinese Agricultural Science Bulletin,2021,37(17):120-128. |
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| Authors: | Jiang Shuo Wan Lu Xu Zhexiang Yan Jiajia Zheng Chunying |
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| Institution: | 1.Engineering Research Center of Agricultural Microbiology Technology, Ministry of Education, Heilongjiang University, Harbin 150500;2.Key Laboratory of Microbiology, College of Heilongjiang Province/School of Life Sciences, Heilongjiang University, Harbin 150080 |
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| Abstract: | To efficiently utilize the flavonoids of Cannabis sativa L and systematically carry out research on flavonoids of Cannabis sativa L, in this study, the structures, synthesis pathways, biological activities and analysis methods of flavonoids of Cannabis sativa L were reviewed. The results showed that 26 flavonoids compounds of Cannabis sativa L were contained in the Cannabis sativa L, and the main structure types of these flavonoids compounds were flavonoids and flavonols. Moreover, based on the classical synthetic pathway of flavonoids, the biosynthesis pathway of cannflavins A and cannflavins B, which were the characteristic flavonoids of Cannabis sativa L., were identified. Meanwhile, the biological activities of Cannabis sativa L, such as anti-tumor, neuroprotective, antidepressant and so on, were also summarized. According to the structural characteristics and biological activities, LC-MS was established as the efficient and rapid method to analyze the flavonoids in Cannabis sativa L. The study could provide certain reference for the research and application of the flavonoids in Cannabis sativa L. |
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| Keywords: | Cannabis sativa L flavonoids structure biological activity synthetic pathway analysis method |
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