The use of eugenol against Aeromonas hydrophila and its effect on hematological and immunological parameters in silver catfish (Rhamdia quelen) |
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| Authors: | Fernando Jonas Sutili Luiz Carlos Kreutz Mirela Noro Leticia Trevisan Gressler Berta Maria Heinzmann Agueda Castagna de Vargas Bernardo Baldisserotto |
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| Institution: | 1. Departamento de Fisiologia e Farmacologia, Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS, Brazil;2. Faculdade de Agronomia e Medicina Veterinária, Universidade de Passo Fundo, 99052-900 Passo Fundo, RS, Brazil;3. Departamento de Medicina Veterinária Preventiva, Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS, Brazil;4. Departamento de Farmácia Industrial, Universidade Federal de Santa Maria, 97105-900 Santa Maria, RS, Brazil |
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| Abstract: | The aim of this study was to evaluate the activity of eugenol against the fish pathogen Aeromonas hydrophila and eugenol's effect on hematological and natural immune parameters in silver catfish (Rhamdia quelen). In vitro, eugenol showed weak activity against A. hydrophila, but in vivo, at a subinhibitory concentration (10 mg L?1), it promoted survival in infected silver catfish. Eugenol (50 μg mL?1) reduced the hemolytic activity of A. hydrophila supernatant in vitro in fish erythrocytes. Subjecting catfish to eugenol baths (5 and 10 mg L?1) for five days did not alter the hematological and immunological parameters studied in this work. Based on these results, eugenol can be used to treat or prevent bacterial diseases in fish. |
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| Keywords: | Innate immune system Fish Silver catfish Bacteria Hematology |
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