| 吡格列酮对冠心病合并糖耐量异常患者冠脉支架内再狭窄的影响 |
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| 引用本文： | 李日健,李上海,吴铿.吡格列酮对冠心病合并糖耐量异常患者冠脉支架内再狭窄的影响[J].湛江医学院学报,2009,27(6):620-623. |
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| 作者姓名： | 李日健 李上海 吴铿 |
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| 作者单位： | 广东医学院附属医院心内科,广东湛江,524001 |
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| 摘 要： | 目的观察吡格列酮对冠心病合并糖耐量异常患者冠脉支架内再狭窄的影响。方法本组97例均为冠心病合并糖耐量异常在我院接受冠脉药物支架置入术的患者,随机分为两组：吡格列酮组（n=46）接受吡格列酮（15mg/d）和基础治疗;对照组（n=51）只接受基础治疗。两组术后均随访6个月,记录支架内再狭窄率和心血管事件发生率。结果在随访期内两组支架内再狭窄发生率,吡格列酮组为（0.51±0.11）%,对照组为（2.84±0.48）%,两组比较差异有统计学意义（P〈0.05）;心血管事件发生率,吡格列酮组也比对照组有显著降低。结论冠心病合并糖耐量异常患者置入支架后服用吡格列酮能有效降低支架内再狭窄和减少心血管事件的发生。
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| 关 键 词： | 吡格列酮 糖耐量异常 支架内再狭窄 |
Effects of pioglitazone on stent restenosis in coronary heart disease patients with impaired glucose tolerance |
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| LI Ri-jian,LI Shang-hai,WU Keng.Effects of pioglitazone on stent restenosis in coronary heart disease patients with impaired glucose tolerance[J].Journal of Guangdong Medical College,2009,27(6):620-623. |
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| Authors: | LI Ri-jian LI Shang-hai WU Keng |
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| Institution: | LI Ri-jian,LI Shang-hai,WU Keng(Department of Cardiology of Guangdong Medical College,Zhanjiang 524001,China) |
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| Abstract: | Objective To observe the effects of pioglitazone on stent restenosis in coronary heart disease patients with impaired glucose tolerance.Methods Ninety-seven percutaneous coronary intervention(PCI) patients with impaired glucose tolerance from March 2006 to March 2008 were randomly divided into pioglitazone group(n=46) receiving conventional therapy plus medication pioglitazone(15mg/day),and control group(n=51) merely receiving conventional therapy.The groups were followed up for six months after operation.T... |
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| Keywords: | pioglitazone impaired glucose tolerance stent restenosis |
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