Insulinoma and Subclinical Peripheral Neuropathy in Two Dogs |
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| Authors: | Kyle G Braund DVM PhD Janet E Steiss DVM PhD Karen A Amling MA Maria Toivio-Kinnucan PhD Lisa C Case DVM Robert J Kemppainen DVM PhD Elaine S Coleman DVM |
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| Institution: | Neuromuscular Laboratory, Scott-Ritchey Research Program, Auburn University, Alabama 36849. |
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| Abstract: | Two dogs with diffuse, subclinical polyneuropathy associated with insulinoma are reported. Seizures were the dominant sign of central nervous system disease. One dog had clinical signs of facial nerve paralysis. Lesions in selected appendicular and cranial nerves included a mixture of demyelination, remyelination, and axonal degeneration. The incidence (range: 18-47%) of these changes far exceeded that of comparable nerves from six control dogs (range 0-11%). Myopathic and electrodiagnostic findings were compatible with the nerve changes. |
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