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红曲合生元、酵母硒锗及其组合对断奶仔猪生长性能、养分表观消化率、血清生化指标的影响
引用本文:高凯,菅芯蕊,耿春银,张敏.红曲合生元、酵母硒锗及其组合对断奶仔猪生长性能、养分表观消化率、血清生化指标的影响[J].中国畜牧兽医,2019,46(9):2583-2591.
作者姓名:高凯  菅芯蕊  耿春银  张敏
作者单位:延边大学农学院, 延吉 133002
基金项目:吉林省重点科技研发项目"肉猪无抗系列饲料的研发与应用"(201802074NY)
摘    要:为研究红曲合生元、酵母硒锗及其组合替代抗生素对断奶仔猪生长性能的影响。试验选用80头平均日龄(28±1)d,平均体重(7.57±0.49)kg,生长健康的三元杂交断奶仔猪,随机分为4个处理组,每组5个重复,每个重复4头仔猪。对照组饲喂基础日粮+25 mg/kg硫酸黏杆菌素和45 mg/kg金霉素,1、2、3组分别在基础日粮中添加0.5%红曲合生元、0.5%红曲合生元酵母硒锗复合制剂、0.5%酵母硒锗制剂。正式试验42 d,分3个阶段(1~14、15~28、29~42 d)。结果显示:①与对照组相比,1、2组各阶段平均日增重(ADG)均显著或极显著升高(P<0.05;P<0.01),各试验组29~42 d的料重比(F/G)显著降低(P<0.05)。各试验组仔猪末重与对照组差异极显著或显著(P<0.01;P<0.05)。②与对照组相比,试验1~7 d,1组腹泻率(DR)和腹泻指数(DI)显著降低(P<0.05);综合试验全期,1组DR、DI及2组DR均显著降低(P<0.05)。与3组相比,1、2组DI指标极显著或显著降低(P<0.01;P<0.05)。③与对照组相比,试验1~28 d,1、2组粗蛋白质(CP)和粗脂肪(EE)表观消化率显著或极显著提高(P<0.05;P<0.01);试验29~42 d,各试验组干物质(DM)、CP和EE表观消化率显著或极显著提高(P<0.05;P<0.01),1、2组总磷(TP)消化率均呈显著提高(P<0.05)。④与对照组相比,试验组血清生长激素(GH)、胰岛素生长因子-1(IGF-1)含量均显著或极显著升高(P<0.05;P<0.01),血清生长抑素(GHRIH)含量显著或极显著下降(P<0.05;P<0.01);其中,2组血清IGF-1含量较1、3组相比显著升高(P<0.05)。与对照组相比,1、2组血清皮质醇(COR)含量均呈显著升高(P<0.05)。综上所述,与抗生素相比,0.5%红曲合生元酵母硒锗复合制剂可预防断奶仔猪腹泻,同时有效地促进断奶仔猪生长发育;该复合制剂可替代日粮中25 mg/kg硫酸黏杆菌素和45 mg/kg金霉素。

关 键 词:红曲合生元  抗生素  酵母硒锗  断奶仔猪  生长性能  
收稿时间:2019-04-01

Effect of Monascus Synbiotic,Yeast-Selenium-Germanium Culture and Their Compound Preparation on Growth Performance,Apparent Digestibility and Serum Biochemistry of Weaned Piglets
GAO Kai,JIAN Xinrui,GENG Chunyin,ZHANG Min.Effect of Monascus Synbiotic,Yeast-Selenium-Germanium Culture and Their Compound Preparation on Growth Performance,Apparent Digestibility and Serum Biochemistry of Weaned Piglets[J].China Animal Husbandry & Veterinary Medicine,2019,46(9):2583-2591.
Authors:GAO Kai  JIAN Xinrui  GENG Chunyin  ZHANG Min
Institution:Department of Animal Science, Yanbian University, Yanji 133002, China
Abstract:This experiment was aimed to study the effects of Monascus synbiotic,yeast-selenium-germanium culture and their compound preparation instead of antibiotics on growth performance of weaned piglets.Eighty healthy piglets (7.57 kg±0.49 kg) with (28±1) d were randomly divided into 4 groups with 5 replicates per group and 4 piglets per replicate.The pigs in control group were fed basal diet with 25 mg/kg colistin sulfate and 45 mg/kg chlortetracycline.The diets of groups 1,2 and 3 were added with 0.5% Monascus synbiotics,0.25% Monascus synbiotics+0.25% yeast-selenium-germanium culture and 0.5% yeast-selenium-germanium culture.The test period was 42 d,which was divided into 3 stages,14 days per stage (1-14,15-28,29-42 d).The results showed that:①Compared with the control group,in all stages of the experiment,the ADG of the groups 1 and 2 were significant or extremely significant increased (P<0.05;P<0.01).At 29-42 d,the F/G of all the experimental groups were significantly decreased (P<0.05).Compared with the control group,the final weight of piglets in the experimental groups had extremely significant or significant increased (P<0.01;P<0.05).②Compared with the control group,the diarrhea rate (DR) and diarrhea index (DI) of the group 1 were significantly decreased (P<0.05) on the 1-7 d of the experiment.In the whole trial period,compared with the control group,the DR and DI of the group 1 and the DR of the group 2 were significantly lower (P<0.05).Compared with the group 3,the DI of the group 1 and 2 showed an extremely significant or significant decrease (P<0.01;P<0.05).③Compared with the control group,the apparent digestibility of CP and EE of the groups 1 and 2 were significantly or extremely significantly increased (P<0.05;P<0.01) at the 1-28 d of the experiment.Compared with the control group,the apparent digestibility of DM,CP and EE of all the experimental groups were significantly or extremely significantly increased (P<0.05;P<0.01),and the apparent digestibility of P of the groups 1 and 2 were significantly increased (P<0.05) on the 29-42 d of the experiment.④Compared with the control group,the serum GH and IGF-1 levels of all the experimental groups were significantly or extremely significantly increased (P<0.05;P<0.01),and the serum GHRIH of all the experimental groups was significantly or extremely significantly decreased (P<0.05;P<0.01).Among them,the serum IGF-1 level of the group 2 was significantly higher than that in the groups 1 and 3 (P<0.05).Compared with the control group,the serum COR levels of the groups 1 and 2 were significantly increased (P<0.05).In summary,compared with antibiotics,0.5% compound preparation of Monascus synbiotic and yeast-selenium-germanium culture could effectively prevent diarrhea in weaned piglets and improve the growth of weaned piglets.The 0.5% Compound Preparation of Monascus synbiotic and yeast-selenium-germanium culture could replace 25 mg/kg colistin sulfate and 45 mg/kg aureomycin in diet under this experiment.
Keywords:Monascus ynbiotics  antibiotics  yeast-selenium-germanium culture  weaned piglets  growth performance  
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