| 细菌活载体及其在寄生虫疫苗研究上的应用 |
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| 引用本文： | 彭高辉,剡海阔,刘苗苗,朱兴全,袁子国.细菌活载体及其在寄生虫疫苗研究上的应用[J].中国畜牧兽医,2010,37(1):88-90. |
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| 作者姓名： | 彭高辉 剡海阔 刘苗苗 朱兴全 袁子国 |
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| 作者单位： | （华南农业大学兽医学院， 广州 510642） |
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| 基金项目： | 国家公益性行业(农业)科研专项经费项目资助(200803017);;教育部“长江学者和创新团队发展计划”创新团队项目(IRT0723);;广东省高等学校自然科学研究重点项目(06Z004)联合资助 |
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| 摘 要： | 随着重组DNA技术的发展和应用,基因工程疫苗的研究取得了快速的进展。减毒或无毒的活微生物作为疫苗载体能够激起持久的系统和黏膜免疫反应,且具有易于接种、安全和廉价等特点,近年来已成为疫苗研究领域的热点。作者对细菌活载体及其在寄生虫疫苗研究上的应用作一概述,从而为研制新型寄生虫疫苗提供参考。
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| 关 键 词： | 细菌活载体 寄生虫 疫苗 |
The Bacterial Carriers and their Applications in the Development of Vaccines against Parasites |
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| PENG Gao-hui,YAN Hai-kuo,LIU Miao-miao,ZHU Xing-quan,YUAN Zi-guo.The Bacterial Carriers and their Applications in the Development of Vaccines against Parasites[J].China Animal Husbandry & Veterinary Medicine,2010,37(1):88-90. |
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| Authors: | PENG Gao-hui YAN Hai-kuo LIU Miao-miao ZHU Xing-quan YUAN Zi-guo |
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| Institution: | (College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China) |
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| Abstract: | With the development of recombinant DNA technology,rapid progress has been made in genetically engineered vaccines.Live recombinant bacteria can induce both mucosal and systemic immune responses against heterologous antigens,which are easy to vaccinate,safe and cost effective.In recent years,using live bacteria as vaccine vectors are becoming hot topic in the field of vaccine studies and development.In this review,the bacterial carriers and their application in the development of vaccines against parasites ... |
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| Keywords: | live bacteria vaccine vectors parasite vaccines |
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