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复方党参口服液对小鼠免疫功能的影响
引用本文:牛瑞燕,阎小艳,王俊东.复方党参口服液对小鼠免疫功能的影响[J].山西农业科学,2008,36(9).
作者姓名:牛瑞燕  阎小艳  王俊东
作者单位:山西农业大学动物科技学院,山西,太谷,030801
摘    要:为探讨复方党参口服液对小鼠免疫功能的影响,将40只健康昆明系小鼠随机分成对照组、低剂量组、中剂量组和高剂量组,每组10只,分别灌服生理盐水,口服液浓度为0.5,1.0,1.5 g/ml,各0.1 ml/只.d。试验10 d后,测定小鼠脾脏系数、胸腺系数和体增重(试验第11 d时与0 d时小鼠体重的差值),并进行脾脏的组织形态学观察;测定各组小鼠腹腔巨噬细胞的吞噬功能以及红细胞免疫功能。结果表明,复方党参口服液可显著增加小鼠脾脏系数,升高小鼠腹腔巨噬细胞吞噬百分率和吞噬指数。初步证明复方党参口服液对正常小鼠的免疫功能有较强的促进和调节作用。

关 键 词:中药  复方党参口服液  免疫功能

Effect of Compound Codonopsis Oral Liquids to Immunity Function in Mice
NIU Rui-yan,YAN Xiao-yan,WANG Jun-dong.Effect of Compound Codonopsis Oral Liquids to Immunity Function in Mice[J].Journal of Shanxi Agricultural Sciences,2008,36(9).
Authors:NIU Rui-yan  YAN Xiao-yan  WANG Jun-dong
Abstract:To study the effects of compound codonopsis oral liquids to immunity function in mice,40 healthy Kunming mice were randomly divided into 4 groups of 10 mice in each.With one untreated group as the control to give the normal saline 0.1 ml/d;the other three groups were administrated with respectively low dose in their drinking water(0.5 g/ml),middle dose(1.0 g/ml),and high dose(1.5 g/ml).10 days later immune organs' weight,weight gain,celiac macrophage phagocytosis and the red cell immunity function were detected,and splenic histology was studied by microscope.Results showed that compared with the control group,spleen index were increased significantly.Additionally,compound codonopsis oral liquids highly enhanced E-C3bRR of mice and decreased E-ICRR significantly.Therefore,it is proved primarily that compound codonopsis oral liquids can influence and regulate the immunity of normal mice.
Keywords:Traditional Chinese medicine  Compound codonopsis oral liquids  Immunity function
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