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Polypeptide with broad biological activity: isolation from small intestine |
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| Authors: | S I Said V Mutt |
| Abstract: | A polypeptide, which has potent and diverse biological action-including systemic vasodilation, hypotension, increased cardiac output, respiratory stimulation, and hyperglycemia-was isolated from the small intestine of the hog. The peptide has 28 amino acid residues and is chemically distinct from the kinins, "substance P," glucagon, and secretin. |
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