| 复方中药口服液抗腹泻作用机理研究 |
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| 引用本文： | 兰新财,;赵丽丽,;叶志惠,;吴叶锋,;姜正前.复方中药口服液抗腹泻作用机理研究[J].中兽医医药杂志,2014(6):19-21. |
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| 作者姓名： | 兰新财 ;赵丽丽 ;叶志惠 ;吴叶锋 ;姜正前 |
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| 作者单位： | [1]浙江金大康动物保健品有限公司,浙江金华321016; [2]金华职业技术学院生物工程学院,浙江金华321017 |
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| 基金项目： | 金华市科技局重点科研项目“防治高死亡率哺乳仔猪腹泻中药制剂的研发”（项目编号：2012-2-004） |
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| 摘 要： | 目的：研究复方中药口服液抗腹泻的作用机理。方法：以发病仔猪病料（小肠及内容物）、蓖麻油和番泻叶分别对小鼠灌胃,后灌服复方中药口服液,研究复方中药口服液对小鼠攻毒后的保护作用。结果：病料攻毒后小鼠的主要病理变化在肝、胆及小肠,复方中药口服液对病料和蓖麻油灌胃致小鼠腹泻具有明显的治疗作用。结论：复方中药口服液抗腹泻作用主要表现在对小肠的保护作用。
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| 关 键 词： | 仔猪 腹泻 中药口服液 作用机理 |
Research on the mechanism of compound TCM oral liquid against diarrhea |
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| Institution: | LAN Xin-cai. ZHAO Li-li, YE Zhi-hui, WU Ye-feng, JIANG Zheng-qian (1.Zhejiang Jindkcom Animal Health Business CO., LTD.. Jinhua Zhejiang 321016;2. Department of Bio-Engineering of Jinhua Polytechnic. Jinhua Zhejiang 321017, China) |
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| Abstract: | Objective： To study the mechanism of compound TCM oral liquid against diarrhea. Methods： Mice were intragastric administrated with compound TCM oral liquid after giving small intestine contents of piglets suffering from diarrhea, castor-il and Folium Sennae. respectively. Then their therapeutical effects were observed. Results： Liver, gall, small intestine of mice appeared main pathological feature after challenged with small intestine of infected piglets. Compound TCM oral liquid could obviously protect mice from diarrhea caused by pathogen and castor oil. Conclusion： The main mechanism of compound TCM oral liquid against diarrhea is protecting small intestine. |
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| Keywords: | piglet： diarrhea： compound TCM oral liquid mechanism |
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