| 米邦塔仙人掌黄酮提取物的急性毒性试验研究 |
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| 引用本文： | 朱凯,梁桂英.米邦塔仙人掌黄酮提取物的急性毒性试验研究[J].吉林农业科技学院学报,2014(4):8-10. |
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| 作者姓名： | 朱凯 梁桂英 |
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| 作者单位： | 长春师范大学生命科学学院,长春130032 |
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| 基金项目： | 吉林省科技厅科研项目（201205047） |
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| 摘 要： | 为探讨米邦塔仙人掌黄酮提取物对小鼠的急性毒性作用,试验采用改良寇氏法,一次性给予小鼠灌胃不同剂量的米邦塔仙人掌黄酮提取物,观察和记录7d内小鼠的死亡率和中毒反应,计算该提取物的急性半数致死量LD50。结果显示：米邦塔仙人掌黄酮提取物对小鼠的LD50为10.24g/kg,95%可信限为8.32~12.60g/kg。结论：急性毒性试验表明该提取物对小鼠实际无毒。
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| 关 键 词： | 米邦塔仙人掌 黄酮类物质 急性毒性 小鼠 |
Study on the Acute Toxicity Test of Flavonoids Extracts in Opuntia milpa alta Haw |
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| ZHU Kai,LIANG Guiying.Study on the Acute Toxicity Test of Flavonoids Extracts in Opuntia milpa alta Haw[J].Journal Of Jilin Agricultural Science And Technology College,2014(4):8-10. |
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| Authors: | ZHU Kai LIANG Guiying |
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| Institution: | ( Changchun Normal University School of Life Sciences, Changchun 130032 ) |
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| Abstract: | In order to explore the acute toxicity factions of flavonoids extracts in Opuntia milpa alta Haw to mice, Used the modified Karber＇s method, the extracts were treated with different oral doses in mice at one time. By observing and recording the mortality and toxic reaction of mice within 7 days, calculated the median lethal dose（LD50） of the flavonoids extracts. The results showed that the LD50 of flavonoids＇ extractso in Opuntia milpa alta Haw to mice was 10.24g/kg, the 95% confidence limit was 8.32~ 12.60g/kg.The acute toxicity test showed that the extracts were actually non-toxic on mice. |
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| Keywords: | Opuntia milpa alta Haw flavonoids acute toxicity mice |
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