| 鸡肾型传染性支气管炎(IB)疫苗的研制 |
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| 引用本文： | 陆苹,孙建和,李晖,王欣,孙涛,张红燕,王国丰.鸡肾型传染性支气管炎(IB)疫苗的研制[J].上海交通大学学报(农业科学版),2000,18(1):4-7. |
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| 作者姓名： | 陆苹 孙建和 李晖 王欣 孙涛 张红燕 王国丰 |
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| 作者单位： | 上海交通大学,上海市兽医生物技术重点实验室,上海,201101 |
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| 基金项目： | 上海市科技发展基金(963213012) |
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| 摘 要： | 用鸡传染性支气管炎病毒X株接种10日龄鸡胚尿囊腔，收集尿囊液，经甲醛灭活后，按一定的比例，以矿物油为佐剂制成油乳剂灭活苗，免疫鸡30d后，保护率达100％，并呈现良好的体液免疫应答，血凝抑制抗体效价达2
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| 关 键 词： | 鸡肾型传染性支气管炎 疫苗 免疫保护 抗体应答 |
| 文章编号： | 1000-193X(2000)-01-0004-04 |
| 修稿时间： | 2000-01-20 |
Preparation and evaluation of infectious bronchitis virus(nephrosis form) vaccine |
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| LU Ping,SUN Jian-he,LI Hui,WANG Xin,SUN Tao,ZHANG Hong-yan,WANG Guo-feng.Preparation and evaluation of infectious bronchitis virus(nephrosis form) vaccine[J].Journal of Shanghai Jiaotong University (Agricultural Science),2000,18(1):4-7. |
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| Authors: | LU Ping SUN Jian-he LI Hui WANG Xin SUN Tao ZHANG Hong-yan WANG Guo-feng |
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| Institution: | LU Ping ,SUN Jian-he ,LI Hui ,WANG
Xin ,SUN Tao ,ZHANG Hong-yan ;
(Key Lab of Velerinary Bio-technology, Shanghai Jiaotong Univ.,Shanghai 201101,China) |
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| Abstract: | A strain of IBV(nephrosis form) was ampilfied and the vaccine was prepared with formalinized allantoic fluid.220 chicken(1 month old) were immunized with the vaccine at different dose by muscle injection.One month later,100%protection were induced after challenging with the same strain,an enhanced and prolonged antibody response was confirmed by hemagglutination inhibition test (HI) and virus neutralization test(VN).Moreover,the vaccine showed absolute safety and high stability. |
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| Keywords: | IBV vaccine immunoprotection antibody response |
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