| 皖南黑猪CETP基因单核苷酸多态检测与遗传分析 |
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| 引用本文： | 何小雷,余大华,黄龙,朱朋,吴涛,陈亮,丁月云,殷宗俊.皖南黑猪CETP基因单核苷酸多态检测与遗传分析[J].安徽农业大学学报,2013,40(5):706. |
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| 作者姓名： | 何小雷 余大华 黄龙 朱朋 吴涛 陈亮 丁月云 殷宗俊 |
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| 作者单位： | 安徽农业大学动物科技学院，安徽地方畜禽遗传资源保护与生物育种省级实验室，合肥 230036,安徽安泰农业集团，广德 242200,安徽农业大学动物科技学院，安徽地方畜禽遗传资源保护与生物育种省级实验室，合肥 230036,安徽农业大学动物科技学院，安徽地方畜禽遗传资源保护与生物育种省级实验室，合肥 230036,安徽农业大学动物科技学院，安徽地方畜禽遗传资源保护与生物育种省级实验室，合肥 230036,安徽农业大学动物科技学院，安徽地方畜禽遗传资源保护与生物育种省级实验室，合肥 230036,安徽农业大学动物科技学院，安徽地方畜禽遗传资源保护与生物育种省级实验室，合肥 230036,安徽农业大学动物科技学院，安徽地方畜禽遗传资源保护与生物育种省级实验室，合肥 230036 |
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| 基金项目： | 国家自然科学基金（31171200）, 科技富民强县专项行动计划, 国家农业科技成果转化资金（2011GB2C300017）, 省级农业科技专家大院（2012）和科技部星火计划重点项目（2010GA710001）共同资助。 |
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| 摘 要： | 以 112头皖南黑猪为研究对象，采用PCR-SSCP方法检测胆固醇酯转运蛋白（cholesteryl ester transfer protein，CETP）基因的多态性。结果表明：(1) 皖南黑猪CETP基因第1内含子795碱基处发生C→T突变（C795T）；(2) 在C795T突变位点中检测到CC、CT、TT 3种基因型，其基因型频率分别为0.6250、0.3036和0.0714；C的基因频率为0.7768，T的基因频率为0.2232；(3) 皖南黑猪CETP基因的多态信息含量（PIC）为0.2866，该位点处于中度多态；卡方检验表明，该位点的χ2值为1.7388，处于哈迪-温伯格平衡状态。
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| 关 键 词： | 皖南黑猪 CETP基因 单核苷酸多态 遗传分析 |
Single nucleotide polymorphism detection and genetic analysis of CETP gene in Wannan Black Pig |
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| HE Xiao-lei,YU Da-hu,HUANG Long,ZHU Peng,WU Tao,CHEN Liang,DING Yue-yun and YIN Zong-jun.Single nucleotide polymorphism detection and genetic analysis of CETP gene in Wannan Black Pig[J].Journal of Anhui Agricultural University,2013,40(5):706. |
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| Authors: | HE Xiao-lei YU Da-hu HUANG Long ZHU Peng WU Tao CHEN Liang DING Yue-yun and YIN Zong-jun |
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| Institution: | Anhui?Provincial?Key?Laboratory?of?Local?Livestock?and?Poultry?Genetic?Resources?Conservation?and?Bio-Breeding, School of Animal Science and Technology, Anhui Agricultural University, Hefei 230036,Anhui Antai Agriculture Group, Guangde 242200,Anhui?Provincial?Key?Laboratory?of?Local?Livestock?and?Poultry?Genetic?Resources?Conservation?and?Bio-Breeding, School of Animal Science and Technology, Anhui Agricultural University, Hefei 230036,Anhui?Provincial?Key?Laboratory?of?Local?Livestock?and?Poultry?Genetic?Resources?Conservation?and?Bio-Breeding, School of Animal Science and Technology, Anhui Agricultural University, Hefei 230036,Anhui?Provincial?Key?Laboratory?of?Local?Livestock?and?Poultry?Genetic?Resources?Conservation?and?Bio-Breeding, School of Animal Science and Technology, Anhui Agricultural University, Hefei 230036,Anhui?Provincial?Key?Laboratory?of?Local?Livestock?and?Poultry?Genetic?Resources?Conservation?and?Bio-Breeding, School of Animal Science and Technology, Anhui Agricultural University, Hefei 230036,Anhui?Provincial?Key?Laboratory?of?Local?Livestock?and?Poultry?Genetic?Resources?Conservation?and?Bio-Breeding, School of Animal Science and Technology, Anhui Agricultural University, Hefei 230036 and Anhui?Provincial?Key?Laboratory?of?Local?Livestock?and?Poultry?Genetic?Resources?Conservation?and?Bio-Breeding, School of Animal Science and Technology, Anhui Agricultural University, Hefei 230036 |
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| Abstract: | |
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| Keywords: | Wannan Black pig CETP gene single nucleotide polymorphism genetic analysis |
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