| 德州驴GDF10基因多态鉴定及其与生长性状的关联分析 |
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| 引用本文： | 白福霞,李梅,裴浩宇,安小娅,王刚,王延涛,于杰,党瑞华.德州驴GDF10基因多态鉴定及其与生长性状的关联分析[J].中国牛业科学,2022,48(1):65-72. |
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| 作者姓名： | 白福霞 李梅 裴浩宇 安小娅 王刚 王延涛 于杰 党瑞华 |
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| 作者单位： | 西北农林科技大学动物科技学院,陕西 杨凌712100,山东东阿阿胶公司,山东 东阿252299 |
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| 基金项目： | 陕西省重点研发计划（2020NY-002）；延安市科技计划项目（2019ZDQY-018, 2019ZDQY-005, 2019ZDQY-016）；东阿阿胶公司项目(20191001)；国家自然科学基金面上项目（81770514) |
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| 摘 要： | 目的]研究将生长/分化因子-10(GDF10)作为候选基因,探讨其多态与不同性别的德州驴生长性状之间的关系.方法]通过对440头德州驴进行多态检测,鉴定得到3个SNPs位点,并对SNP位点进行分型.利用SPSS 18.0软件分析3个SNPs位点的不同基因型与德州驴9个生长性状的关联分析.结果]结果显示,3个位点均...
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| 关 键 词： | 德州驴 GDF10基因 SNP 生长性状 |
| 收稿时间： | 2021/11/7 0:00:00 |
| 修稿时间： | 2021/11/17 0:00:00 |
Polymorphism of GDF10 gene and its Association with Growth Traits in Dezhou Donkeys |
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| Bai fuxi,Li mei,Pei haoyu,An xiaoy,Wang gang,Wang Yantao,Yu Jie and Dang Ruihua.Polymorphism of GDF10 gene and its Association with Growth Traits in Dezhou Donkeys[J].China Cattle Science,2022,48(1):65-72. |
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| Authors: | Bai fuxi Li mei Pei haoyu An xiaoy Wang gang Wang Yantao Yu Jie and Dang Ruihua |
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| Institution: | College of Animal Science and Technology,Northwest A F University,Yangling,,,,,,,College of Animal Science and Technology,Northwest A F University,Yangling |
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| Abstract: | Objective]In this study, growth/differentiation factor-10 (GDF10) was selected as a candidate gene to explore the association between GDF10 polymorphism and growth traits of Dezhou donkeys of different genders. Method] In 440 Dezhou donkeys, 3 SNPs were detected, and were genotyped. SPSS 18.0 software was used to analyze the association between three genotypes at different SNP loci and nine growth traits of Dezhou donkeys. Result]The results showed that the three loci were in hardy-Weinberg equilibrium (P> 0.05); analysis of population genetic parameters showed that there is a high degree of homogeneity in the polymorphic loci of GDF10 gene, and the content of polymorphic information was moderate (0.25< PIC< 0.50). The results of association analysis showed that in jennies, the rump high of AA genotype was significantly higher than that of GA genotype at g.2031481 A>G locus (P < 0.05), at g.2041898A>G locus, the body height and rump length of AA genotype were significantly higher than those of GA genotype (P< 0.05), and at g. 2043035 C>T locus, the rump length of CC genotype was significantly higher than that of CT genotype (P < 0.05). In jackasses, the body height of CC genotype at the G. 2043035 C>T locus was significantly lower than that of CT genotype (P < 0.05). Conclusion]In conclusion, GDF10 gene polymorphism is related to the growth traits of Dezhou donkeys and can be used as a molecular marker for the growth and development of Dezhou donkeys. |
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| Keywords: | Dezhou donkeys GDF10 gene SNP growth traits |
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