| 普洱茶不同溶剂提取组分降脂减肥作用的比较研究 |
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| 引用本文： | 熊昌云,彭远菊,王兴华,崔文锐,李凤娟,何普明.普洱茶不同溶剂提取组分降脂减肥作用的比较研究[J].茶叶科学,2012,32(6):543-551. |
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| 作者姓名： | 熊昌云 彭远菊 王兴华 崔文锐 李凤娟 何普明 |
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| 作者单位： | 1. 浙江大学茶学系,浙江 杭州 310058; 2. 云南热带作物职业学院热作系,云南 普洱 665000; 3. 普洱市茶树良种场,云南 普洱 665000 |
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| 基金项目： | 中央财政支持重点专业建设项目 |
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| 摘 要： | 采用丙酮、水、氯仿、乙酸乙酯和正丁醇连续萃取普洱茶,旋转蒸发后冷冻干燥得到氯仿层、乙酸乙酯层、正丁醇层以及剩余水层4个主要分离组分,利用不同的组分灌胃经过肥胖造模处理的ICR小鼠,与普洱茶总水提取物和减肥药左旋肉碱进行比较,研究普洱茶不同组分对ICR肥胖小鼠的降脂减肥作用。实验结果表明,普洱茶总水提取物、乙酸乙酯萃取组分、剩余水层组分均对肥胖ICR小鼠具有很好的降脂减肥作用。其中乙酸乙酯层和剩余水层抑制脂肪累积（抑制率分别是24.7%和22.5%）的效果略差于减肥药物左旋肉碱（抑制率38.8%）,但在改善血清指标尤其是提高HDL-C水平方面（提高率为61.7%和73.4%）显著优于左旋肉碱（9.4%）,肝脏指标检测也得到了类似的结论,揭示普洱茶降脂减肥作用的主要成分可能存在于乙酸乙酯层和（或）剩余水层中。
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| 关 键 词： | 普洱茶 组分 降脂减肥 左旋肉碱 |
| 收稿时间： | 2012-05-21 |
Comparative Study on Lipid-lowering and Anti-obesity Effect of Different Pu-erh Tea Fractions |
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| XIONG Chang-yun
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PENG Yuan-ju
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WANG Xing-hua
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CUI Wen-rui
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LI Feng-juan
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HE Pu-ming.Comparative Study on Lipid-lowering and Anti-obesity Effect of Different Pu-erh Tea Fractions[J].Journal of Tea Science,2012,32(6):543-551. |
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| Authors: | XIONG Chang-yun PENG Yuan-ju WANG Xing-hua CUI Wen-rui LI Feng-juan HE Pu-ming |
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| Institution: | 1. Department of Tea Science, Zhejiang University, Hangzhou 310058, China; 2. Department of Tropical Crops, Yunnan Vocational College of Tropical Crops, Puer 665000, China; 3. Tea Seed Multiplication Farm of Puer, Puer 665000, China |
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| Abstract: | In this study,Pu-erh tea was extracted with acetone,water,chloroform,ethyl acetate,and n-butanol.then,the extraction was concentrated with rotary evaporation and dried with lyophilizer into chloroform layer,ethyl acetate layer,n-butanol layer and surplus water layer extracts,which were used to administer ICR obese mouse for analyzing the lipid-lowering and anti-obesity effects.The experimental results demonstrated that the pu-erh tea total extract,ethyl acetate extract and surplus water extract are all effective on lipid-lowering and anti-obesity of ICR obese mouse,and the effects of ethyl acetate extract and surplus water extract on inhibiting fat accumulation(inhibition ratio was 24.7% and 22.5%)was slightly less than those in the L-carnitine(38.8%),but the effect on improving HDL-C level(61.7% and 73.4%) significantly superior to that in the L-carnitine(9.4%),the similar results were obtained in the mice liver,which suggest that the key lipid-lowering and anti-obesity function components were existed in the ethyl acetate layer and(or) surplus water layer extracts of pu-erh tea. |
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| Keywords: | pu-erh tea fractions lipid-lowering and anti-obesity L-carnitine |
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