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猪围产期外周血ANAE+T细胞动态观察
引用本文:梁宏德,程相朝,宁长申.猪围产期外周血ANAE+T细胞动态观察[J].畜牧兽医学报,2002,33(5):517-519.
作者姓名:梁宏德  程相朝  宁长申
作者单位:1. 河南农业大学牧医工程学院,郑州,450002
2. 河南洛阳农业高等专科学校,洛阳,471003
基金项目:国家自然科学基金资助项目 ( 39370 5 19)
摘    要:有用酸性α-醋酸萘酯酶(ANAE)染色方法测定了11头猪围产期外周血不同时期总ANAE^ T与大颗粒型ANAE^ T细胞(tANAE^ T细胞与lgANAE^ T细胞)百分率,结果表明,猪分娩前21d至分娩前6d,外周血tANAE^ T细胞与lgANAE^ T细胞百分率均低于分娩后第25d的相应指标,说明猪妊娠后期细胞免疫功能低下;分娩前10d,猪外周血tANAE^ T细胞与lgANAE^ T细胞百分率均较分娩前第21d的相应指标显著升高(P<0.05),提示分娩的启动可能与母体细胞免疫功能增强,导致免疫排斥的发生有一定关系,分娩后tANAE^ T细胞与lgANAE^ T细胞百分率降低后逐渐升高,tANAE^ T细胞分娩后第10d,lgANAE^ T细胞于分娩后第5d已分别明显高于猪分娩前第21d的相应指标(P<0.05),猪分娩后第25d的tANAE^ T细胞与lgANAE^ T细胞和正常未妊娠母猪的相应指标接近,表明猪分娩后5-25d细胞免疫功能已渐恢复正常。

关 键 词:  围产期  外周血  ANAE^+T细胞  动态变化  免疫状态  免疫机理
文章编号:0366-6964(2002)05-0517-03

Dynamics of Peripheral Blood ANAE+T Cells During the Peripartum in Sows
LIANG Hong-de ,CHENG Xiang-chao,NING Chang-shen.Dynamics of Peripheral Blood ANAE+T Cells During the Peripartum in Sows[J].Acta Veterinaria et Zootechnica Sinica,2002,33(5):517-519.
Authors:LIANG Hong-de  CHENG Xiang-chao  NING Chang-shen
Institution:LIANG Hong-de 1,CHENG Xiang-chao,NING Chang-shen 1
Abstract:By using acid a-naphthyl acetate esterase(ANAE) staining,the percentanges of peripheral blood total ANAE +T cell (tANAE +T cell) and large granule ANAE +T cell (lgANAE +T cell) during peripartum in 11 sows were assayed.The results indicated that:From the 21st day to the 6th day before parturition,the percentages of peripheral blood tANAE +T cells and lgANAE +T cells were significaltly lower than those on the 25th day after parturition,which shown that the cellular immune function was in a lower state in the late pregnancy period.The percentages of peripheral blood tANAE +T cell and lgANAE +T cell were apparently increased on the 1st day before parturition,which suggested that the starting of parturition seems to be related to the increased cellular immune function.The percentages of tANAE +T cell and lgANAE +T cell in peripheral blood were decreased in the few early days after parturition and then increased gradually,the percentage of tANAE +T cell on the 10th day and the percentage of lgANAE +T cell on the 5th day after parturition were much higher than those on the 21st day before parturition,which shown that the rates of tANAE +T cell and lgANAE +T cell in these days had reached the physiological level basically.
Keywords:Sow  Peripartum  ANAE  +T cell
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