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An association exists between bovine herpesvirus-4 seropositivity and abortion in cows
Authors:G Czaplicki and E Thiry
Institution:

a Centre de Dépistage des Maladies Animales, Avenue A. Deponthière, 40, B-4431, Loncin, Belgium

b Virology, Faculty of Veterinary Medicine, University of Liège, B 43bis Sart Tilman, B-4000, Liege, Belgium

Abstract:The prevalence of cattle seropositive to bovine herpesvirus-4 (BHV-4) is high in Belgium. In Belgian farms, clinical signs associated with BHV-4 infection essentially involve the genital tract and consist mainly of postpartum metritis or metroperitonitis. The role of BHV-4 in abortion has not been definitively demonstrated but epidemiological and experimental facts suggest its involvement. A seroepidemiological investigation was therefore conducted as a case-control study to compare the seroprevalences of BHV-4 infections in the aborted-cow population and in a randomly selected control group in the province of Liège (Belgium). The seroprevalence (17.2%) in aborted cows was significantly higher than that of the control group (10.0%). The odds ratio (OR) was 1.87 (1.06 < 3.30). BHV-4 infection is therefore considered as a risk factor for abortion in cows.
Keywords:Cattle microbiological disease  Bovine herpesvirus-4  Abortion  Case-control study
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