| 特比萘酚对白念珠菌Cahxt5缺失株表型的影响 |
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| 引用本文： | 王娟,周二鹏,贾鹏飞.特比萘酚对白念珠菌Cahxt5缺失株表型的影响[J].动物医学进展,2011,32(5):69-71. |
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| 作者姓名： | 王娟 周二鹏 贾鹏飞 |
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| 作者单位： | 石家庄学院化工学院,河北石家庄,050035 |
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| 基金项目： | 石家庄市科学技术研究与发展指导计划项目，石家庄学院博士基金项目 |
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| 摘 要： | 应用倍比稀释方法,分析了白念珠菌CaHXT5缺失株细胞在特比萘酚处理下的袁型,同时检测了特比萘酚对该缺失株细胞菌丝形成的影响效应.结果表明,与野生型相比,CaHXT5缺失株细胞对75μg/mL的特比萘酚敏感,该浓度的特比萘酚能够明显抑制该缺失株细胞菌丝形成和致病力.
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| 关 键 词： | 白念珠菌 CaHXT5蛋白 特比萘酚 表型 |
Effects of Terbinafine on Phenotypes of Candida abbicans Cahxt5 Deletion Mutant |
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| WANG Juan,ZHOU Er-peng,JIA Peng-fei.Effects of Terbinafine on Phenotypes of Candida abbicans Cahxt5 Deletion Mutant[J].Progress In Veterinary Medicine,2011,32(5):69-71. |
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| Authors: | WANG Juan ZHOU Er-peng JIA Peng-fei |
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| Institution: | (College of Chemical Engineering,Shijiazhuang University,Shijiazhuang,Hebei,050035,China) |
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| Abstract: | Phenotype effect of Candida albicans Cahxt5 cell was analyzed on serial plates containning gradient concentration terbinafine.At the same time,the effective perturbation caused by hexose transporter,CaHXT5 protein,through filament formation was detected.The results showed that Cahxt5 deleted cells was sensitive to 75 μg/mL terbinafine,and the filament formation and virulence of the deletion strain were obviously inhibited by this concentration terbinafine. |
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| Keywords: | Candida albicans CaHXT5 protein terbinafine phenotype |
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