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Sesquiterpene lactones from Centaurea musimomum. Antiplasmodial and cytotoxic activities
Authors:Medjroubi Kamel  Benayache Fadila  Bermejo Jaime
Institution:1. College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China;2. Key Laboratory of Environment Correlative Food Science, Ministry of Education, Huazhong Agricultural University, Wuhan 430070, China;1. National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA;2. School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong
Abstract:The chloroform extract of the aerial parts of Centaurea musimomum exhibited significant activity against Plasmodium falciparum. The phytochemical study of this extract gave seven native and four acetylated sesquiterpene lactones.
Keywords:Centaurea musimomum  Sesquiterpene lactones  Antiplasmodial activity  Cytotoxic activity
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