| 顶复门原虫入侵相关因子的研究进展 |
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| 引用本文： | 戚南山,孙铭飞,廖申权,吴彩艳,吕敏娜,袁建丰,余劲术,李祥瑞,蔡建平.顶复门原虫入侵相关因子的研究进展[J].畜牧兽医学报,2012,43(2):167-174. |
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| 作者姓名： | 戚南山 孙铭飞 廖申权 吴彩艳 吕敏娜 袁建丰 余劲术 李祥瑞 蔡建平 |
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| 作者单位： | 1. 广东省农业科学院兽医研究所,广州,510640
2. 南京农业大学动物医学院,南京,210095 |
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| 基金项目： | NSFC-广东联合基金 |
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| 摘 要： | 顶复门原虫是一类专一性的细胞内寄生原虫,包括弓形虫(Toxoplasma gondii)、隐孢子虫(Cryptosporidium spp.)、疟原虫(Plasmodium spp.)、巴贝斯虫(Babesia spp.)及艾美耳球虫(Eimeria spp.)等,是人和动物的重要病原.这类原虫具有相似的亚细胞结构和保守的入侵机制.研究结果表明,入侵过程是由大量的入侵相关蛋白分子所介导的,包括微线、棒状体及致密颗粒所分泌的相关蛋白等.随着生物信息学及分子生物学的发展,顶复门原虫入侵相关蛋白分子的研究资料也日益增多.笔者结合最近几年本课题组的研究成果,综述了顶复门原虫入侵相关蛋白因子的最新进展.
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| 关 键 词： | 顶复门原虫 入侵机制 入侵相关因子 |
Invasion-associated Factors of Apicomplexa |
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| QI Nan-shan
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SUN Ming-fei
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LIAO Shen-quan
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WU Cai-yan
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LV Min-na
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YUAN Jian-feng
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YU Jing-shu
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LI Xiang-rui
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CAI Jian-ping.Invasion-associated Factors of Apicomplexa[J].Acta Veterinaria et Zootechnica Sinica,2012,43(2):167-174. |
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| Authors: | QI Nan-shan SUN Ming-fei LIAO Shen-quan WU Cai-yan LV Min-na YUAN Jian-feng YU Jing-shu LI Xiang-rui CAI Jian-ping |
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| Institution: | 1(1.Institute of Veterinary Medicine,Guangdong Academy of Agricultural Sciences, Guangzhou 510640,China;2.Department of Preventive Veterinary Medicine,College of Veterinary Medicine,Nanjing Agricultural University,Nanjing 210095,China) |
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| Abstract: | Apicomplexa is a protozoan class of obligate intracellular parasites,including Toxoplasma gondii,Cryptosporidium spp.,Plasmodium spp.,Babesia spp.and Eimeria spp.,many of them are important pathogens to human and animal.They have conserved subcellular structures and invasion mechanism.The results of lots of researches demonstrate that the invasion mechanisms are mediated by many invasion-associated factors,including the proteins secreted from micronemes,rhoptries and dense granules.The researches about these proteins make great progress with the development of bioinformatics and biotechnologies.In this paper,we review the latest progress of invasion-associated factor combining with our research results in recent years. |
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| Keywords: | Apicomplexa invasion mechanism invasion-associated factor |
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