| 不同粒径粉碎对葛根主要有效成分葛根素溶出影响的研究 |
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| 引用本文： | 刘蕊,戴娜桑,李健,马玉芳,黄一帆.不同粒径粉碎对葛根主要有效成分葛根素溶出影响的研究[J].中兽医医药杂志,2011,30(1):40-44. |
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| 作者姓名： | 刘蕊 戴娜桑 李健 马玉芳 黄一帆 |
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| 作者单位： | 福建农林大学动物科学学院,福建福州,350002 |
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| 摘 要： | 葛根经普通粉碎和超微粉碎后加工成40-65、65-100、100-200、200-300目不同粒径粉末,分别用水和30%乙醇提取,高效液相色谱法（HPLC）测定葛根素的含量,比较不同粒径葛根粉中有效成分葛根素溶出率的差异。结果其水提葛根素含量分别为2.68%、2.95%、3.03%、3.13%、3.20%;醇提葛根素含量分别为3.10%、3.17%、3.35%、3.55%、3.66%。该结果表明,随着葛根粉碎粒径的变小,葛根素的溶出率显著提高,醇提葛根素的含量明显高于水提葛根素。
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| 关 键 词： | 葛根 葛根素 不同粉碎粒径 溶出度 HPLC |
Effect of different particle size on the dissolubility of main active ingredients puerarin in Redix pueraria |
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| LIU Rui,DAI Na-sang,LI Jian,MA Yu-fang,HUANG Yi-fan.Effect of different particle size on the dissolubility of main active ingredients puerarin in Redix pueraria[J].Journal of Traditional Chinese Veterinary Medicine,2011,30(1):40-44. |
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| Authors: | LIU Rui DAI Na-sang LI Jian MA Yu-fang HUANG Yi-fan |
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| Institution: | (College of Animal Science,Fujian Agriculture and Forestry University, Fuzhou Fujian 350002,China) |
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| Abstract: | The dissolution of main active ingredients puerarin in Redix pueraria of different particle was studied in this paper.Redix pueraria was made into ordinary powder and ultra-fine powder with particles of 40-65 mesh,65-100 mesh,100-200 mesh,200-300 mesh and more than 300 mesh,respectively.Cotents of puerarin from different particles treated with water and 30% of ethanol were determined by high performance liquid chromatography（HPLC）.The results were as following： the contents of puerarin from aboved particles were 2.68%,2.95%,3.03%,3.13%,and 3.20% respectively after treated with water,and 3.10%,3.17%,3.35%,3.55%,3.66% respectively after treated with methanol.The results showed that dissolubility of puerarin in Redix pueraria was increased with decreasing particle size and the content of purrarin in Redix pueraria treated with methanol were higher than that of treated with water. |
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| Keywords: | HPLC |
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