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鸡传染性支气管炎疫苗对雏鸡的多重免疫研究
引用本文:杨增岐,张淑霞,赵余放.鸡传染性支气管炎疫苗对雏鸡的多重免疫研究[J].西北农林科技大学学报(社会科学版),2002,30(4):101-104.
作者姓名:杨增岐  张淑霞  赵余放
作者单位:1. 西北农林科技大学动物科技学院,陕西杨陵,712100
2. 榆林市畜牧兽医中心,陕西榆林,719000
基金项目:杨陵农业科技开发基金项目 (96JK-13 )
摘    要:将 2 0 0只 1日龄健康雏鸡随机分为 6组 ,第 1~ 5组分别用 H1 2 0 、H52 和 IB二价油佐剂灭活苗进行单独或多重组合的免疫接种 ,于接种后每隔 7d测 1次 HI抗体 ,并于第 73天用肾型 IBV强毒攻击 ,观察各组的保护率 ,第 6组不免疫作为对照。结果显示 ,H1 2 0 弱毒苗单独免疫组、H1 2 0 +IB二价油佐剂灭活苗组、H1 2 0 +H52 弱毒苗组、IB二价油苗 1次免疫组和 IB二价油苗 2次免疫组的保护率分别为 5 7.1% ,85 .8% ,6 7% ,83.3%和 80 % ,非免疫对照组保护率为 5 0 %。试验结果表明 ,H1 2 0 与 H52 弱毒苗对肾型 IBV的保护力弱 ,H1 2 0 +IB二价油佐剂灭活疫苗与 IB二价油佐剂灭活苗 1次和 2次免疫均可获得对肾型 IBV较高的保护率 ,且 H1 2 0 与 IB二价油佐剂灭活苗同时免疫可获得长时间的保护性抗体

关 键 词:鸡传染性支气管炎  弱毒疫苗  油佐剂灭活疫苗  HI抗体
文章编号:1000-2782(2002)04-0101-04
收稿时间:2002/1/24 0:00:00
修稿时间:2002年1月24日

Multi-vaccinated study of chickens inoculated with avian infectious bronchitis vaccines
YANG Zeng qi ,ZHANG Shu xia ,ZHAO Yu fang ,PAN Rui ,JIANG Yan fen ,HE Yu sheng ,LIU Jian peng.Multi-vaccinated study of chickens inoculated with avian infectious bronchitis vaccines[J].Journal of Northwest Sci-Tech Univ of Agr and,2002,30(4):101-104.
Authors:YANG Zeng qi  ZHANG Shu xia  ZHAO Yu fang  PAN Rui  JIANG Yan fen  HE Yu sheng  LIU Jian peng
Institution:YANG Zeng qi 1,ZHANG Shu xia 1,ZHAO Yu fang 1,PAN Rui 1,JIANG Yan fen 1,HE Yu sheng 2,LIU Jian peng 2
Abstract:one day old chicks were divided into 6 groups.Group 1-5 were inoculated lonely or multiplely with Avian Infectious Bronchitis(IB) vaccines which including attenuated Virus of H 120 and H 52 strain as well as bivalent oil emulsion inactivated Vaccine(OEV).Group 6 was not inoculated as control test.Anti IBV antibody titers of the 6 groups of chickens were tested by hemagglutination inhibition (HI) test once a week after inoculation.Chickens were challenged with virulent IBV at the 73th day after inoculation.The protective rates of the 6 groups were observed.The results showed that the protective rates of H 120 lonely inoculated group,H 120 +IB OEV group,H 120 +H 52 group,IB OEV inoculated one time and two times group as well as control group were 57.1%,85.8%,67%,83.3%,80% and 50%,respectively.The protective rate of H 120 and H 52 strain was lower than IB OEV.Although chickens inoculated with H 120 +IB OEV,IB OEV one time and two times all got higher protective rate,chickens inoculated with H 120 strain and IB OEV simultaneously could get longer protective period than the other two groups.
Keywords:Avian infectious bronchitis  attenuated vaccine  oil emulsion inactivated vaccine  HI antibody
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