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Transanal pull-through rectal amputation for treatment of colorectal carcinoma in 11 dogs |
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| Authors: | Morello Emanuela Martano Marina Squassino Chiara Iussich Selina Caccamo Roberta Sammartano Federica Zabarino Sara Bellino Claudio Pisani Guido Buracco Paolo |
| Institution: | Dipartimento di Patologia Animale, School of Veterinary Medicine, Turin, Italy |
| Abstract: | Objective— To evaluate outcome after transanal rectal pull-through amputation of single colorectal adenocarcinoma and in situ carcinoma (T is ) in dogs. Study Design— Retrospective case series. Animals— Dogs (n=11) with colorectal cancer. Methods— Full-thickness colorectal amputation by either simple transanal (7 dogs) or combined abdominal–transanal (4) pull-through technique. Results— Adenocarcinoma (8) and T is (2) were removed with 3–6 cm of grossly normal tissue, cranial and caudal to the tumor, or in 1 T is with 2 cm grossly normal tissue, cranial and caudal. Two dogs that had a combined abdominal–transanal approach died within 4 days. In the other dogs, postoperative complications included short-term tenesmus (6 dogs), rectal bleeding (11), rectal stricture (3), and long-term fecal incontinence (1). Postoperative recurrence and metastatic rates for adenocarcinoma were 18.2% and 0%, respectively. Median disease-free interval and survival time were not reached. Mean disease-free and overall survival times were 44.3 and 44.6 months (range, 0–75 months), respectively. Conclusion— En bloc excision of colorectal T is and adenocarcinoma may be followed by a long survival. Complications of the transanal approach are usually moderate and self-limiting, but complications are more common and severe when more extensive resections are performed through a combined abdominal–transanal approach. Clinical Relevance— Transanal rectal pull-through amputation is suitable for en bloc resection of colorectal neoplasia. A combined abdominal–transanal approach should be reserved for tumors extending from the mid-cranial region of the rectum to the descending colon. |
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