| 静脉注射纤维素微粒诱发肉鸡腹水综合征模型的建立 |
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| 引用本文： | 李英,曾健滢,潘家强,韩前彪,李玉谷.静脉注射纤维素微粒诱发肉鸡腹水综合征模型的建立[J].中国兽医学报,2011,31(2). |
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| 作者姓名： | 李英 曾健滢 潘家强 韩前彪 李玉谷 |
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| 作者单位： | 华南农业大学,兽医学院,广东,广州,510642 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 通过翅静脉注射CM-32纤维素微粒,观察血清白蛋白(ALB)、总蛋白(TP)、血细胞压积(PCV)、血红蛋白(Hb)、腹水等方面的变化,探讨建立肉鸡腹水综合征(AS)模型的可行性。试验分为2组,试验组在20日龄时注射0.3 mL纤维素悬液,对照组注射等量生理盐水。饲养期间统计临床型AS的发病率,并分别于21、28、35、42日龄从各组随机抽样,测定右心/全心重量比值(RV/TV),检查ALB、TP、PCV、Hb、腹水液等。结果试验组AS发病率(12%)显著高于对照组(3.3%),RV/TV值显著增加。纤维素微粒阻塞在肺血管,引起明显的炎性细胞聚集和肉芽结缔组织增生。试验组血清ALB、TP在42日龄明显低于对照组,PCV在28、35日龄时显著高于对照组(P<0.05),Hb在35日龄时显著高于对照组(P<0.05),其腹水液为典型的漏出液,表明翅静脉注射CM-32纤维素微粒成功诱发了AS。
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| 关 键 词： | 纤维素微粒 腹水综合征 肉鸡 |
Establishment of ascites syndrome model by intravenous injection of cellulose particles |
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| LI Ying,ZENG Jian-ying,PAN Jia-qiang,HAN Qian-biao,LI Yu-gu.Establishment of ascites syndrome model by intravenous injection of cellulose particles[J].Chinese Journal of Veterinary Science,2011,31(2). |
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| Authors: | LI Ying ZENG Jian-ying PAN Jia-qiang HAN Qian-biao LI Yu-gu |
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| Institution: | LI Ying,ZENG Jian-ying,PAN Jia-qiang,HAN Qian-biao LI Yu-gu(College of Veterinary Medicine,South China Agricultural University,Guangzhou 510642,China) |
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| Abstract: | Broiler AS was induced by intravenous injection of cellulose particles though wing vein.Packed cell volume(PCV),hemoglobin(Hb),serum albumin(ALB),total protein(TP),ascites were measuered for evaluating the feasibility of this method of inducing AS.Broilers were divided into 2 groups,the experimental group and the control group.Broilers of experimental group were intravenously injected with 0.3 mL CM-32 cellulose suspension at 20-day-old,while the control group under the same conditions were intravenously in... |
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| Keywords: | cellulose particles ascites syndrome broiler |
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