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传染性囊病抗原-抗体复合苗免疫雏鸡的效果
引用本文:毕英佐,曹永长,吕英姿,龙丽萍,史孔云.传染性囊病抗原-抗体复合苗免疫雏鸡的效果[J].华南农业大学学报,2000,21(1):75-77.
作者姓名:毕英佐  曹永长  吕英姿  龙丽萍  史孔云
作者单位:华南农业大学动物科学系,广东,广州,510642
摘    要:用IBDV抗体与某IBD商品疫苗民IBDV-Ab复合苗,用IBDV-Ab复活 合苗与IBD商品疫苗在有母源抗体的雏鸡中进行免疫对比试验,试验鸡随机分为4组,饲养在隔离器中,第1组为空白对照组,第2组为攻毒对照组,第3组在10d龄用复合苗进行免疫第4组在10d龄用商品苗进行免疫、各组从11d龄起每隔10d采血,用酶联免疫吸附试验检测血清中IBD抗体水平,35d龄时进行攻毒试验,试验结果显示,21d龄

关 键 词:传染性法氏囊病  免疫    抗原抗体复合苗  疫苗
修稿时间:1999-05-07

Efficacy of Infectious Bursal Disease (IBD) Virus-Antibody Vaccine on Broiler Chickens with Maternal Antibodies
BI Ying-zuo,CAO Yong-chang,L Ying-zi,LONG Li-ping,SHI Kong-yun.Efficacy of Infectious Bursal Disease (IBD) Virus-Antibody Vaccine on Broiler Chickens with Maternal Antibodies[J].Journal of South China Agricultural University,2000,21(1):75-77.
Authors:BI Ying-zuo  CAO Yong-chang  L Ying-zi  LONG Li-ping  SHI Kong-yun
Institution:BI Ying-zuo,CAO Yong-chang,L(U) Ying-zi,LONG Li-ping,SHI Kong-yun
Abstract:The efficacy of a novel vaccine, infectious bursal disease virus-antibody complex vaccine (IBDV-Ab), was compared with that of a commercial IBDV vaccine in Shiqiza broiler with maternal antibodies against IBDV. Seventy-five birds were divided into four groups and raised in isolation units. Birds of group 3 and 4 were vaccinated at 10 days with IBDV-Ab vaccine and commercial vaccine, respectively, whereas chickens of group 1 and 2 were not vaccinated with any vaccine. The antibodies against IBDV were measured by enzyme-linked immunosorbent assay (ELISA) before and after vaccinations. All the broilers of groups 2, 3, 4 were challenged with a virulent IBDV strain at 35 days of age. The mean ELISA titres (ET) of group 3 and 4 at 21 days of age were 738 and 946, respectively, and these at 31 days of age were 2 403 and 1 700. After challenge, mortality of groups 2, 3 and 4 were 50% 1 5% and 10% , respectively. The results showed that the efficacy of vaccination with IBDV-Ab vaccine was better than that with commercial vaccine. The data herein suggested that being mixed with antibody against IBDV increase the efficacy of IBDV live vaccine.
Keywords:infectious bursal disease  IBDV-antibody complex vaccine  vaccination
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